Now showing items 1-10 of 115
Improvement of Pro-Oxidant Capacity of Protocatechuic Acid by Esterification
(Plos One, 2014-10-23) [Artigo]
Pro-oxidant effects of phenolic compounds are usually correlated to the one-electron redox potential of the phenoxyl radicals. Here we demonstrated that, besides their oxidizability, hydrophobicity can also be a decisive ...
New drugs with antiprotozoal activity from marine algae: a review
(Revista Brasileira de Farmacognosia, 2014-06-01) [Artigo]
The use of indigenous or remote popular knowledge to identify new drugs against diseases or infections is a well-known approach in medicine. The inhabitants of coastal regions are known to prepare algae extracts for the ...
Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines
(Stem Cells, 2013-12-01) [Artigo]
Hotair is a member of the recently described class of noncoding RNAs called lincRNA (large intergenic noncoding RNA). Various studies suggest that Hotair acts regulating epigenetic states by recruiting chromatin-modifying ...
Fabrication of microenvironments with different geometrical features for cell growth studies
(Journal Of Laser Micro Nanoengineering, 2014-11-01) [Artigo]
Studies of cell development in artificial microenvironments can contribute to understanding a series of physiological mechanisms that might be influenced by geometrical features of the microenvironment itself. In this work ...
Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
(PLOS ONE, 2013-04-25) [Artigo]
Background: Diffuse astrocytomas are the most common type of primary brain cancer in adults. They present a wide variation in differentiation and aggressiveness, being classified into three grades: low-grade diffuse ...
Effect of soybean yoghurt supplemented with isoflavones on the haemolytic activity of serum complement in mice with experimental lung metastasis of murine mammary and pulmonary adenocarcinoma
(Annual Review of Biomedical Sciences, 2005) [Artigo]
The malate synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin
(BMC Microbiology, 2009-12-24) [Artigo]
Background: The pathogenic fungus Paracoccidioides brasiliensis is the agent of paracoccidioidomycosis (PCM). This is a pulmonary mycosis acquired by inhalation of fungal airborne propagules that can disseminate to several ...
Candida parapsilosis complex water isolates from a haemodialysis unit: biofilm production and in vitro evaluation of the use of clinical antifungals
(Memórias do Instituto Oswaldo Cruz, 2011-09-01) [Artigo]
Candida parapsilosis, currently divided into three distinct species, proliferates in glucose-rich solutions and has been associated with infections resulting from the use of medical devices made of plastic, an environment ...
Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility
(BMC Infectious Diseases, 2014-06-12) [Artigo]
Background: Group B Streptococcus (GBS) remains a major cause of neonatal sepsis and is also associated with invasive and noninvasive infections in pregnant women and non-pregnant adults, elderly and patients with underlying ...
Antitumor and antimycobacterial activities of cyclopalladated complexes: X-ray structure of [Pd(C-2,N-dmba)(Br)(tu)] (dmba = N,N-dimethylbenzylamine, tu = thiourea)
(European Journal of Medicinal Chemistry, 2009-11-01) [Artigo]
The reactions between [Pd(C-2,N-dmba)(mu-X)](2) (dmba = N,N-dimethylbenzylamine: X = Cl, Br) and thiourea (tu) in the 1:2 molar ratio at room temperature resulted in the mononuclear compounds [Pd(C-2,N-dmba)(Cl)(tu)] (1) ...