Now showing items 1-10 of 11
Alkaloids extracted from Pterogyne nitens induce apoptosis in malignant breast cell line
(Tumor Biology, 2010-10-01) [Artigo]
In the present study, two alkaloids isolated from Pterogyne nitens, a plant native to Brazil, have been shown to induce apoptosis in human breast cancer cells. These compounds, pterogynine (PGN) and pterogynidine (PGD), ...
Caffeic Acid Phenethyl Ester: Consequences of Its Hydrophobicity in the Oxidative Functions and Cytokine Release by Leukocytes
(Evidence-based Complementary And Alternative Medicine, 2014-01-01) [Artigo]
Numerous anti-inflammatory properties have been attributed to caffeic acid phenethyl ester (CAPE), an active component of propolis. NADPH oxidases are multienzymatic complexes involved in many inflammatory diseases. Here, ...
Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage
(Journal Of Ethnopharmacology, 2015-08-27) [Artigo]
Garcinia brasiliensis, a plant native to the Brazilian Amazon Rainforest, is used in traditional medicine to treat inflammation of the urinary tract, peptic ulcers, arthritis and other conditions. The purposes of this study ...
Alkyl caffeates as anti-helicobacter pylori and scavenger of oxidants produced by neutrophils
(Medicinal Chemistry, 2014-02-01) [Artigo]
Helicobacter pylori pathogenic action involves the colonization of the gastrointestinal tract and a large production of reactive oxygen species (ROS) by the neutrophils attracted to the site of infection. The aim of this ...
4 '-Aminochalcones as novel inhibitor of the chlorinating activity of myeloperoxidase
(Planta Medica, 2012-08-01) [Resumo]
Apocynin: Chemical and biophysical properties of a NADPH oxidase inhibitor
(Molecules, 2013-03-01) [Artigo]
Apocynin is the most employed inhibitor of NADPH oxidase (NOX), a multienzymatic complex capable of catalyzing the one-electron reduction of molecular oxygen to the superoxide anion. Despite controversies about its ...
Inhibitory Effect of Gallic Acid and Its Esters on 2,2 '-Azobis(2-amidinopropane)hydrochloride (AAPH)-Induced Hemolysis and Depletion of Intracellular Glutathione in Erythrocytes
(Journal of Agricultural and Food Chemistry, 2010-05-12) [Artigo]
The protective effect of gallic acid and its esters, methyl, propyl, and lauryl gallate, against 2,2'-azobis(2-amidinopropane)hydrochloride (AAPH)-induced hemolysis and depletion of intracellular glutathione (GSH) in ...
Biologically Active Eremophilane-Type Sesquiterpenes from Camarops sp., an Endophytic Fungus Isolated from Alibertia macrophylla
(Journal of Natural Products, 2014-03-01) [Artigo]
Two new eremophilane-type sesquiterpenes, xylarenones F (3) and G (4), have been isolated from solid substrate cultures of a Camarops sp. endophytic fungus isolated from Alibertia macrophylla, together with the known ...
Bioactive Secondary Metabolites from Phomopsis sp., an Endophytic Fungus from Senna spectabilis
(Molecules, 2014-05-01) [Artigo]
Chemical investigation of an acetonitrile fraction from the endophytic fungus Phomopsis sp. led to the isolation of the new natural product 2-hydroxy-alternariol (7) together with the known compounds cytochalasins J (1) ...
Ethyl Ferulate, a Component with Anti-Inflammatory Properties for Emulsion-Based Creams
(Molecules, 2014-06-01) [Artigo]
Ethyl ferulate (FAEE) has been widely studied due to its beneficial heath properties and, when incorporated in creams, shows a high sun protection capacity. Here we aimed to compare FAEE and its precursor, ferulic acid ...