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Assessment of the chemopreventive effect of casearin B, a clerodane diterpene extracted from Casearia sylvestris (Salicaceae)
(Food and Chemical Toxicology, 2013-03-01) [Artigo]
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against ...
Microplate alamarblue assay for paracoccidioides susceptibility testing
(Journal of Clinical Microbiology, 2013-04-01) [Artigo]
CLSI method M27-A3 is not available for use with dimorphic fungi, such as those of the Paracoccidioides genus. In this study, we developed a microdilution method and added the alamarBlue reagent to test the responses of ...
Avaliação do estresse oxidativo no sangue de consumidores habituais de suco de laranja
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2011-11-14) [Artigo]
Two biomarkers of oxidative stress were evaluated in healthy volunteers treated with daily doses of orange juice that is well known source of vitamin C and citric flavanones, which have been associated with antioxidant, ...
The β-chemokines MIP-1α and RANTES and lipoprotein metabolism in HIV-infected Brazilian patients
(Brazilian Journal of Infectious Diseases, 2005-08-01) [Artigo]
HIV patients are predisposed to the development of hypertriglyceridemia and hypercholesterolemia as a result of both viral infection and HIV infection therapy, especially the protease inhibitors. Chemokines and cytokines ...
Lipid peroxidation and antioxidant capacity of G6PD-deficient patients with A-(202G>A) mutation
(Genetics and Molecular Research, 2009-12-01) [Artigo]
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an enzymopathy in which reduced NADPH concentrations are not maintained, resulting in oxidative damage. We evaluated G6PD activity, oxidative stress levels and Trolox ...
Characterization of myeloid or lymphoid acute leukemia by a chemiluminescence assay: Comparison with immunocytochemistry using an antimyeloperoxidase antibody
(Acta Haematologica, 1993-01-01) [Artigo]
A simple and sensitive chemiluminescence assay for the demonstration of the activity of intracellular myeloperoxidase (MPO) is described, which is useful for the distinction between myeloid and lymphoid commitment in blasts ...
Oxidative stress in diabetes and periodontitis
(North American Journal of Medical Sciences, 2013-01-01) [Artigo]
Determination of neutral polymorphisms (frameworks) of the human beta globin gene in beta thalassaemias by PCR/DGGE
(Sangre, 1997-02-01) [Artigo]
Purpose: Considering the importance of type beta thalassaemias as hereditary syndromes of high significance in different populations of Mediterranean origin and, by extension, in the Brazilian population, the objective of ...
An approach to local immunotoxicity induced by adjuvanted vaccines
(International Immunopharmacology, 2013-09-27) [Artigo]
The occurrence of injection site reactions following immunization is the most frequently reported toxicity manifestation of vaccines; however, the different types of local reactions and the different mechanisms involved ...
IL-12 and neutralization of endogenous IL-10 revert the in vitro antigen-specific cellular immunosuppression of paracoccidioidomycosis patients
(Cytokine, 2002-07-25) [Artigo]
Treatment of patients with paracoccidioidomycosis is still a challenge. Patients present defective lymphoproliferation and IFN-γ responses to the main Paracoccidioides brasiliensis antigen (gp43), which correlates with ...