Informamos que as validações de submissão estarão suspensas de 20/12/2019 a 05/01/2020, devido ao recesso de final de ano
Search
Now showing items 1-10 of 11
Alchornea glandulosa Ethyl Acetate Fraction Exhibits Antiangiogenic Activity: Preliminary Findings from In Vitro Assays Using Human Umbilical Vein Endothelial Cells
(Journal of Medicinal Food, 2011-10-01) [Artigo]
Alchornea glandulosa has traditionally been used in Brazilian folk medicine for the treatment of immune-inflammatory diseases and as an antiulcer agent to heal gastric ulcer and gastritis. Angiogenesis is a complex multistep ...
Saponinas antifúngicas de Swartzia langsdorffii
(Química Nova, 2008-01-01) [Artigo]
Chromatographic fractionation of the EtOH extract from the leaves of Swartzia langsdorffii afforded the pentacyclic triterpenes oleanolic acid and lupeol, and two saponins: oleanolic acid 3-sophoroside and the new ester ...
Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi
(Evidence-based Complementary And Alternative Medicine, 2014-01-01) [Artigo]
This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida ...
Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage
(Journal Of Ethnopharmacology, 2015-08-27) [Artigo]
Garcinia brasiliensis, a plant native to the Brazilian Amazon Rainforest, is used in traditional medicine to treat inflammation of the urinary tract, peptic ulcers, arthritis and other conditions. The purposes of this study ...
Anti-angiogenic effects of pterogynidine alkaloid isolated from Alchornea glandulosa
(BMC Complementary and Alternative Medicine, 2009-05-22) [Artigo]
Background: Angiogenesis, a complex multistep process that comprehends proliferation, migration and anastomosis of endothelial cells (EC), has a major role in the development of pathologic conditions such as inflammatory ...
Biologically Active Eremophilane-Type Sesquiterpenes from Camarops sp., an Endophytic Fungus Isolated from Alibertia macrophylla
(Journal of Natural Products, 2014-03-01) [Artigo]
Two new eremophilane-type sesquiterpenes, xylarenones F (3) and G (4), have been isolated from solid substrate cultures of a Camarops sp. endophytic fungus isolated from Alibertia macrophylla, together with the known ...
Bioactive Secondary Metabolites from Phomopsis sp., an Endophytic Fungus from Senna spectabilis
(Molecules, 2014-05-01) [Artigo]
Chemical investigation of an acetonitrile fraction from the endophytic fungus Phomopsis sp. led to the isolation of the new natural product 2-hydroxy-alternariol (7) together with the known compounds cytochalasins J (1) ...
Improvement of Pro-Oxidant Capacity of Protocatechuic Acid by Esterification
(Plos One, 2014-10-23) [Artigo]
Pro-oxidant effects of phenolic compounds are usually correlated to the one-electron redox potential of the phenoxyl radicals. Here we demonstrated that, besides their oxidizability, hydrophobicity can also be a decisive ...
Suppression of TNF- induced NFB activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention
(Natural Product Research, 2010-01-01) [Artigo]
Gallic acid (3,4,5-trihydroxybenzoic acid), found in many plants either in free-form or part of tannins, is known to possess anti-microbial, antioxidant and cytotoxic properties. NFB regulates the expression of several ...
Antifungal Activity of Maytenin and Pristimerin
(Evidence-based Complementary and Alternative Medicine, 2012-01-01) [Artigo]
Fungal infections in humans have increased alarmingly in recent years, particularly in immunocompromised individuals. Among the infections systemic candidiasis, aspergillosis, cryptococcosis, paracoccidioidomycosis, and ...