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Topical Application of Retinyl Palmitate-Loaded Nanotechnology-Based Drug Delivery Systems for the Treatment of Skin Aging
(BioMed Research International, 2014-01-01) [Artigo]
The objective of this study was to perform a structural characterization and evaluate the in vitro safety profile and in vitro antioxidant activity of liquid crystalline systems (LCS) with and without retinyl palmitate ...
Synthesis and biological evaluation of ternary silver compounds bearing N,N-chelating ligands and thiourea: X-ray structure of [{Ag(bpy) (mu-tu)}(2)](NO3)(2) (bpy=2,2 '-bipyridine; tu = thiourea)
(Polyhedron, 2014-09-05) [Artigo]
Compounds [{Ag(phen)(mu-tu)}(2)](NO3)(2) (1), [{Ag(phen)(mu-tu)}(2)](CF3SO3)(2) (2), [{Ag(bpy)(mu-tu)}(2)](NO3)(2) (3) (where phen = 1,10-phenanthroline; bpy = 2,2'-bipyridine; tu = thiourea) were prepared by reacting the ...
Effect of different pre-irradiation times on curcumin-mediated photodynamic therapy against planktonic cultures and biofilms of Candida spp
(Archives of Oral Biology, 2013-02-01) [Artigo]
Objectives: The aim of this study was to evaluate the effects of pre-irradiation time (PIT) on curcumin (Cur)-mediated photodynamic therapy (PDT) against planktonic and biofilm cultures of reference strains of Candida ...
Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
(PLOS ONE, 2013-04-25) [Artigo]
Background: Diffuse astrocytomas are the most common type of primary brain cancer in adults. They present a wide variation in differentiation and aggressiveness, being classified into three grades: low-grade diffuse ...
Microplate alamarblue assay for paracoccidioides susceptibility testing
(Journal of Clinical Microbiology, 2013-04-01) [Artigo]
CLSI method M27-A3 is not available for use with dimorphic fungi, such as those of the Paracoccidioides genus. In this study, we developed a microdilution method and added the alamarBlue reagent to test the responses of ...
Avaliação do estresse oxidativo no sangue de consumidores habituais de suco de laranja
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2011-11-14) [Artigo]
Two biomarkers of oxidative stress were evaluated in healthy volunteers treated with daily doses of orange juice that is well known source of vitamin C and citric flavanones, which have been associated with antioxidant, ...
Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines
(Stem Cells, 2013-12-01) [Artigo]
Hotair is a member of the recently described class of noncoding RNAs called lincRNA (large intergenic noncoding RNA). Various studies suggest that Hotair acts regulating epigenetic states by recruiting chromatin-modifying ...
Fabrication of microenvironments with different geometrical features for cell growth studies
(Journal Of Laser Micro Nanoengineering, 2014-11-01) [Artigo]
Studies of cell development in artificial microenvironments can contribute to understanding a series of physiological mechanisms that might be influenced by geometrical features of the microenvironment itself. In this work ...
Assessment of the chemopreventive effect of casearin B, a clerodane diterpene extracted from Casearia sylvestris (Salicaceae)
(Food and Chemical Toxicology, 2013-03-01) [Artigo]
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against ...
Influence of Fc gamma RIIIb polymorphism on its ability to cooperate with Fc gamma RIIa and CR3 in mediating the oxidative burst of human neutrophils
(Human Immunology, 2014-08-01) [Artigo]
Considering that human neutrophil Fc gamma RIIa and Fc gamma RIIIb receptors interact synergistically with CR3 in triggering neutrophil functional responses, allelic polymorphisms in these receptors might influence such ...