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Estudo fitoquímico de goiaba (Psidium guajava L.) com potencial antioxidante para o desenvolvimento de formulação fitocosmética
(Revista Brasileira de Farmacognosia, 2008-09-01) [Artigo]
Considerando-se a qualidade dos fitoterápicos, é importante salientar que a preocupação com esta questão inclui rigoroso acompanhamento das diferentes etapas do desenvolvimento e produção destes produtos, desde a coleta ...
Topical Application of Retinyl Palmitate-Loaded Nanotechnology-Based Drug Delivery Systems for the Treatment of Skin Aging
(BioMed Research International, 2014-01-01) [Artigo]
The objective of this study was to perform a structural characterization and evaluate the in vitro safety profile and in vitro antioxidant activity of liquid crystalline systems (LCS) with and without retinyl palmitate ...
Synthesis and biological evaluation of ternary silver compounds bearing N,N-chelating ligands and thiourea: X-ray structure of [{Ag(bpy) (mu-tu)}(2)](NO3)(2) (bpy=2,2 '-bipyridine; tu = thiourea)
(Polyhedron, 2014-09-05) [Artigo]
Compounds [{Ag(phen)(mu-tu)}(2)](NO3)(2) (1), [{Ag(phen)(mu-tu)}(2)](CF3SO3)(2) (2), [{Ag(bpy)(mu-tu)}(2)](NO3)(2) (3) (where phen = 1,10-phenanthroline; bpy = 2,2'-bipyridine; tu = thiourea) were prepared by reacting the ...
Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
(PLOS ONE, 2013-04-25) [Artigo]
Background: Diffuse astrocytomas are the most common type of primary brain cancer in adults. They present a wide variation in differentiation and aggressiveness, being classified into three grades: low-grade diffuse ...
Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines
(Stem Cells, 2013-12-01) [Artigo]
Hotair is a member of the recently described class of noncoding RNAs called lincRNA (large intergenic noncoding RNA). Various studies suggest that Hotair acts regulating epigenetic states by recruiting chromatin-modifying ...
Fabrication of microenvironments with different geometrical features for cell growth studies
(Journal Of Laser Micro Nanoengineering, 2014-11-01) [Artigo]
Studies of cell development in artificial microenvironments can contribute to understanding a series of physiological mechanisms that might be influenced by geometrical features of the microenvironment itself. In this work ...
The malate synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin
(BMC Microbiology, 2009-12-24) [Artigo]
Background: The pathogenic fungus Paracoccidioides brasiliensis is the agent of paracoccidioidomycosis (PCM). This is a pulmonary mycosis acquired by inhalation of fungal airborne propagules that can disseminate to several ...
Dispersão de bioaerossóis por aeradores em uma estação de tratamento de esgoto sanitário
(Revista de Ciencias Farmaceuticas, 2004-12-01) [Artigo]
The purpose of this work was to investigate the bioaerosols reach emitted from aerators of the Sanitary Sewage Treatment in Araraquara, Brazil, using the coliform group as indicated microorganisms. The concentration of ...
3,5-Dimethyl-1-thiocarbamoylpyrazole and its Pd(II) complexes: Synthesis, spectral studies and antitumor activity
(European Journal of Medicinal Chemistry, 2010-05-01) [Artigo]
Complexes of the type [PdX(2)(tdmPz)] {X = Cl(-)(1) Br(-)(2); l(-)(3); SCN(-)(4); tdmPz = 1-thiocarbamoy1-3,5-dimethylpyrazole} have been synthesized and characterized. Compound 1 was formed from the reaction between ...
Immunomodulatory Effects of Palladium(II) Complexes of 1,2,4-Triazole on Murine Peritoneal Macrophages
(Journal of the Brazilian Chemical Society, 2009-01-01) [Artigo]
The 1,2,4-triazolyl-bridged polynuclear complexes [{PdCl(2)(mu-Htrz)}(n)] (1) and [{PdBr(2)(mu-Htrz)}(n)] (2) have been obtained in this work. Compound 1 is prepared by the displacement of acetonitrile from [PdCl(2)(MeCN)(2)] ...