Mostrando ítems 1-20 de 696

  • Serodiagnosis

    Mendes-Giannini, Maria José S. Autor UNESP; Del Negro, Gilda Bárbaro; Siqueira, Antonio Martins de (Paracoccidioidomycosis, 2018) [Capítulo de livro]
    Serological methods are of considerable value in paracoccidioidomycosis. Counter-immunoelectrophoresis, otherwise known as electrosyneresis or immunoelectroosmophoresis, has been frequently applied for the immunodiagnosis ...
  • Recent advances in the discovery of small molecules targeting glioblastoma

    Fernandes, Guilherme Felipe dos Santos Autor UNESP; Fernandes, Barbara Colatto Autor UNESP; Valente, Valeria Autor UNESP; dos Santos, Jean Leandro Autor UNESP (European Journal of Medicinal Chemistry, 2019) [Resenha]
    Glioblastoma (GBM) is one of the most common central nervous system cancers. It is characterized as a fast-growing tumor that arises from multiple cell types with neural stem-cell-like properties. Additionally, GBM tumors ...
  • The lncRNA RMEL3 protects immortalized cells from serum withdrawal-induced growth arrest and promotes melanoma cell proliferation and tumor growth

    Cardoso, Cibele; Serafim, Rodolfo B.; Kawakami, Akinori; Gonçalves Pereira, Cristiano; Roszik, Jason; Valente, Valeria Autor UNESP; Vazquez, Vinicius L.; Fisher, David E.; Espreafico, Enilza M. (Pigment Cell and Melanoma Research, 2018) [Artigo]
    RMEL3 is a recently identified lncRNA associated with BRAFV600E mutation and melanoma cell survival. Here, we demonstrate strong and moderate RMEL3 upregulation in BRAF and NRAS mutant melanoma cells, respectively, compared ...
  • Applications of invertebrate animal models to dimorphic fungal infections

    Singulani, Junya L. Autor UNESP; Scorzoni, Liliana Autor UNESP; de Oliveira, Haroldo C. Autor UNESP; Marcos, Caroline M. Autor UNESP; Assato, Patricia A. Autor UNESP; Fusco-Almeida, Ana Marisa Autor UNESP; Mendes-Giannini, Maria José S. Autor UNESP (Journal of Fungi, 2018) [Resenha]
    Dimorphic fungi can be found in the yeast form during infection and as hyphae in the environment and are responsible for a large number of infections worldwide. Invertebrate animals have been shown to be convenient models ...
  • Transcriptional profile of a bioethanol production contaminant Candida tropicalis

    Lourencetti, Natália Manuela Strohmayer Autor UNESP; Wolf, Ivan Rodrigo Autor UNESP; Lacerda, Maria Priscila Franco Autor UNESP; Valente, Guilherme Targino Autor UNESP; Zanelli, Cleslei Fernando Autor UNESP; Santoni, Mariana Marchi Autor UNESP; Mendes-Giannini, Maria José Soares Autor UNESP; Enguita, Francisco Javier; Fusco-Almeida, Ana Marisa Autor UNESP (AMB Express, 2018) [Artigo]
    The fermentation process is widely used in the industry for bioethanol production. Even though it is widely used, microbial contamination is unpredictable and difficult to control. The problem of reduced productivity is ...
  • Influence of eugenia uniflora extract on adhesion to human buccal epithelial cells, biofilm formation, and cell surface hydrophobicity of candida spp. from the oral cavity of kidney transplant recipients

    Souza, Luanda B. F. C.; Silva-Rocha, Walicyranison P.; Ferreira, Magda R. A.; Soares, Luiz Alberto L.; Svidzinski, Terezinha I. E.; Milan, Eveline P.; Pires, Regina H. Autor UNESP; Almeida, Ana Marisa Fusco Autor UNESP; Mendes-Giannini, Maria Jos S. Autor UNESP; Chaves, Guilherme Maranhão (Molecules, 2018) [Artigo]
    This study evaluated the influence of the extract of Eugenia uniflora in adhesion to human buccal epithelial cells (HBEC) biofilm formation and cell surface hydrophobicity (CSH) of Candida spp. isolated from the oral cavity ...
  • Fungal biofilms: Formation, resistance and pathogenicity

    De Cássia Orlandi Sardi, Janaina Autor UNESP; De Souza Pitangui, Nayla Autor UNESP; Gullo, Fernanda Patrícia Autor UNESP; Fusco-Almeida, Ana Marisa Autor UNESP; Mendes-Giannini, Maria Jose Soares Autor UNESP (Medical Mycology: Current Trends and Future Prospects, 2015) [Capítulo de livro]
    Biofilm formation has been detected quite early in the fossil record (~3.25 billion years ago) and is common throughout a diverse range of organisms in both the Archaea and bacteria lineages, including the ‘living fossils’ ...
  • Transcriptomic crosstalk between fungal invasive pathogens and their host cells: Opportunities and challenges for next-generation sequencing methods

    Enguita, Francisco J.; Costa, Marina C.; Fusco-Almeida, Ana Marisa Autor UNESP; Mendes-Giannini, Maria José Autor UNESP; Leitão, Ana Lúcia (Journal of Fungi, 2016) [Resenha]
    Fungal invasive infections are an increasing health problem. The intrinsic complexity of pathogenic fungi and the unmet clinical need for new and more effective treatments requires a detailed knowledge of the infection ...
  • Paracoccidioides brasiliensis 14-3-3 protein is important for virulence in a murine model

    Marcos, Caroline Maria Autor UNESP; de Oliveira, Haroldo Cesar Autor UNESP; Assato, Patricia Akemi Autor UNESP; de Andrade, Cleverton Roberto Autor UNESP; Fusco-Almeida, Ana Marisa Autor UNESP; Mendes-Giannini, Maria José Soares Autor UNESP (Medical mycology, 2019) [Artigo]
    The Paracoccidioides brasiliensis strain downregulated the expression of adhesin Pb14-3-3 (Pb14-3-3 aRNA) was evaluated in a murine model of paracoccidioidomycosis (PCM). Pb14-3-3 aRNA displays attenuated virulence and ...
  • Study of mastoparan analog peptides against Candida albicans and safety in zebrafish embryos (Danio rerio)

    Galeane, Mariana C. Autor UNESP; Gomes, Paulo C. Autor UNESP; L Singulani, Junya de Autor UNESP; de Souza, Bibiana M. Autor UNESP; Palma, Mario S. Autor UNESP; Mendes-Giannini, Maria Js Autor UNESP; Almeida, Ana Mf Autor UNESP (Future microbiology, 2019) [Artigo]
    Aim: In this work, mastoparan analog peptides from wasp venom were tested against Candida albicans and safety assays were performed using cell culture and model zebrafish. Materials & methods: Minimal inhibitory concentration ...
  • Fast removal of Candida parapsilosis from hemodialysis dialysate using ultraviolet or visible light at nanoporous W/WO3 electrodes

    Souza, Barbara A. Autor UNESP; Perini, Joao A. Autor UNESP; Giannini, Maria José S.M. Autor UNESP; Zanoni, Maria Valnice Boldrin Autor UNESP (Journal of Environmental Chemical Engineering, 2019) [Artigo]
    The quality of the water used in a hemodialysis process is critical, and several cases of contamination by C. parapsilosis have been reported in the literature. In addition, it is causing many deaths. The present work ...
  • Prophylactic and therapeutic vaccines against sporotrichosis. Feasibility and prospects

    Téllez-Martínez, Damiana Autor UNESP; Batista-Duharte, Alexander Autor UNESP; Portuondo, Deivys Leandro Autor UNESP; Carlos, Iracilda Zeppone Autor UNESP (Microbes and Infection, 2019) [Artigo]
    Sporotrichosis is an emergent subcutaneous mycosis of humans and some animals caused by dimorphic fungi of the genus Sporothrix. The disease occurs worldwide but is endemic or hyperendemic in tropical and subtropical areas. ...
  • Cryptococcal titan cells: When yeast cells are all grown up

    García-Rodas, Rocío; de Oliveira, Hc Autor UNESP; Trevijano-Contador, Nuria; Zaragoza, Oscar (Current Topics in Microbiology and Immunology, 2019) [Capítulo de livro]
    Cryptococcus neoformans is a human pathogenic yeast that causes hundreds of thousands of deaths worldwide among susceptible individuals, in particular, HIV+ patients. This yeast has developed several adaptation mechanisms ...
  • Curcumin combined with metformin decreases glycemia and dyslipidemia, and increases paraoxonase activity in diabetic rats

    Roxo, Daniela Fernandes Autor UNESP; Arcaro, Carlos Alberto Autor UNESP; Gutierres, Vania Ortega Autor UNESP; Costa, Mariana Campos Autor UNESP; Oliveira, Juliana Oriel Autor UNESP; Lima, Tayra Ferreira Oliveira Autor UNESP; Assis, Renata Pires Autor UNESP; Brunetti, Iguatemy Lourenço Autor UNESP; Baviera, Amanda Martins Autor UNESP (Diabetology and Metabolic Syndrome, 2019) [Artigo]
    Background: Combination of current antidiabetic agents with natural antioxidants to manage diabetes mellitus and its complications has appeared as an emerging trend. Curcumin, a yellow pigment isolated from Curcuma longa ...
  • Identification of Off-Patent Compounds That Present Antifungal Activity against the Emerging Fungal Pathogen Candida auris

    De Oliveira, Haroldo Cesar Autor UNESP; Monteiro, Maria Candida; Rossi, Suélen Andreia; Pemán, Javier; Ruiz-Gaitán, Alba; Mendes-Giannini, Maria José Soares Autor UNESP; Mellado, Emilia; Zaragoza, Oscar (Frontiers in Cellular and Infection Microbiology, 2019) [Artigo]
    Candida auris is an emerging fungal pathogen of great concern among the scientific community because it is causing an increasing number of hospital outbreaks of difficult management worldwide. In addition, isolates from ...
  • In vitro methods to determine the antioxidant activity of caffeic acid

    Spagnol, Caroline Magnani Autor UNESP; Assis, Renata Pires Autor UNESP; Brunetti, Iguatemy Lourenço Autor UNESP; Isaac, Vera Lucia Borges Autor UNESP; Salgado, Hérida Regina Nunes Autor UNESP; Corrêa, Marcos Antonio Autor UNESP (Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2019) [Artigo]
    Caffeic acid (CA) is a plant metabolite acting as a carcinogenic inhibitor, and exhibits a high antioxidant effect and some antimicrobial activity. Besides, this compound can be useful in the prevention of heart diseases ...
  • A recombinant enolase-montanide™ petgel a vaccine promotes a protective th1 immune response against a highly virulent sporothrix schenckii by toluene exposure

    Téllez-Martínez, Damiana Autor UNESP; Portuondo, Deivys Leandro Autor UNESP; Loesch, Maria Luiza Autor UNESP; Batista-Duharte, Alexander Autor UNESP; Carlos, Iracilda Zeppone Autor UNESP (Pharmaceutics, 2019) [Artigo]
    The effect of vaccination in fungal strains that suffered changes in their virulence by exposure to environmental contaminants is largely known. Growing reports of resistance to antifungal drugs and the emergence of new ...
  • Genotoxicity, cytotoxicity and chemical profile from Inga laurina (Fabaceae)

    Falcoski, T. O.R. Autor UNESP; Lima, N. M. Autor UNESP; Navegante, G. Autor UNESP; Serafim, R. B. Autor UNESP; Sorbo, J. M. Autor UNESP; Valente, V. Autor UNESP; Santos, V. N.C.; Santos, R. A.; Silva, D. H.S. Autor UNESP; Soares, C. P. Autor UNESP (Natural Product Research, 2019) [Artigo]
    This study aimed to evaluate the cytotoxicity and genotoxicity from Inga laurina leaves extracts and fractions and obtain their chemical profile. The chemical profile of the crude extract from I. laurina leaves and its ...
  • N, N′ N″-trisubstituted guanidines: Synthesis, characterization and evaluation of their leishmanicidal activity

    do Espírito Santo, Rafael Dias Autor UNESP; Velásquez, Ángela María Arenas Autor UNESP; Passianoto, Luana Vitorino Gushiken Autor UNESP; Sepulveda, Alex Arbey Lopera Autor UNESP; da Costa Clementino, Leandro Autor UNESP; Assis, Renata Pires Autor UNESP; Baviera, Amanda Martins Autor UNESP; Kalaba, Predrag; dos Santos, Fábio Neves; Éberlin, Marcos Nogueira et al. (European Journal of Medicinal Chemistry, 2019) [Artigo]
    Leishmaniasis is a group of diseases caused by protozoan parasites from the genus Leishmania. There are estimated 1.3 million new cases annually with a mortality of 20,000–30,000 per year, when patients are left untreated. ...
  • Curcumin improves the effect of a reduced insulin dose on glycemic control and oxidative stress in streptozotocin-diabetic rats

    Gutierres, Vânia Ortega Autor UNESP; Assis, Renata Pires Autor UNESP; Arcaro, Carlos Alberto Autor UNESP; Oliveira, Juliana Oriel Autor UNESP; Lima, Tayra Ferreira Oliveira Autor UNESP; Beretta, Ana Laura Remédio Zeni; Costa, Paulo Inácio Autor UNESP; Baviera, Amanda Martins Autor UNESP; Brunetti, Iguatemy Lourenço Autor UNESP (Phytotherapy Research, 2019) [Artigo]
    Insulin with natural antioxidants is emerging as a combination treatment for diabetes mellitus that attempts to exert effective glycemic control without adverse effects. The present study aimed to investigate the additive ...