Drug-induced gingival overgrowth: A clinical and histopathological report
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Data
2012-04-01
Autores
Santana Coimbra, L. [UNESP]
Andrade, Cleverton Roberto de [UNESP]
Schneider Herrera, B. [UNESP]
Cirelli, Joni Augusto [UNESP]
Spolidório, Luis Carlos [UNESP]
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Resumo
Gingival overgrowth is a significant problem faced by periodontists and is particularly associated with the use of certain drugs such as nifedipine, a high-specificity calcium channel blocker used for the treatment and prophylaxis of certain cardiovascular diseases. Development of gingival overgrowth is characterized by increased collagen in gingival tissue. In general is asymptomatic, at times associated with spontaneous bleeding and ulceration and can promote aesthetic changes and compromise hygiene habits and mastication of the patient. The severity of the symptoms is associated with the presence of risk factors such association with other drugs. This paper aims to present a case report of a patient with generalized gingival overgrowth, with more severe characteristics in the anterior mandible induced by chronic use of nifedipine who underwent basic non-surgical periodontal treatment including supra and subgingival scaling and root planning in both jaws associated with rigorous oral hygiene instructions and surgical therapy in the anterior mandible, the most affected area, to remove the excess of gingival tissue. Nifedipine was replaced by the patient cardiologist to propanolol hydrochloride (40 mg/kg) in an attempt to minimize unwanted side effects. After 6 month follow-up, no recurrence was observed, oral hygiene had improved and the patient had clinical periodontal health and esthetic satisfaction.
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Palavras-chave
Gingival overgrowth, Nifedipine, Periodontal diseases, therapy, captopril, nifedipine, propranolol, acanthosis, adult, case report, drug induced disease, drug substitution, drug withdrawal, facial nerve paralysis, gingiva bleeding, gingiva overgrowth, gingivectomy, gingivoplasty, human, human tissue, hypertension, male, mouth hygiene, osteolysis, preventive dentistry
Como citar
Chirurgia (Turin), v. 25, n. 2, p. 105-109, 2012.