Artigos - Ciências Biológicas - FCFAR
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Antibacterial activities and antiproliferative assays over a tumor cells panel of a silver complex with 4-aminobenzoic acid: Studies in vitro of sustained release using bacterial cellulose membranes as support
(Journal of Inorganic Biochemistry, 2020) [Artigo]The aims of this work were to evaluate the antibacterial and antiproliferative potential in vitro of the metal complex with 4-aminobenzoic acid (Ag-pABA) and a drug delivery system based on bacterial cellulose (BC-Ag-pABA). ... -
A Critical Review of Analytical Methods for Quantification of Amphotericin B in Biological Samples and Pharmaceutical Formulations
(Critical Reviews in Analytical Chemistry, 2020) [Resenha]Amphotericin B (AmB) is an important antifungal agent available in the clinical practice with the action mechanism related to the inhibition of ergosterol molecule present in the fungal cell wall. Given this, in order to ... -
Phylogenetic and phenotypic relationships of the Triatoma sordida subcomplex (Hemiptera: Reduviidae: Triatominae)
(Acta Tropica, 2020) [Artigo]Chagas disease, whose etiological agent is the protozoan Trypanosoma cruzi, affects millions of people worldwide and it is mainly transmitted by infected triatomine feces. Triatoma is the most diverse genus and one of the ... -
Author Correction: Incorporation of Ursolic Acid in Liquid Crystalline Systems Improves the Antifungal Activity Against Candida sp. (Journal of Pharmaceutical Innovation, (2020), 10.1007/s12247-020-09470-0)
(Journal of Pharmaceutical Innovation, 2020) [Errata]The original version of this article unfortunately contained a mistake. The name of the 3rd author was incorrectly presented. The correct name of the 3rd author is “Matheus Aparecido dos Santos Ramos.”. -
Mutational data and population profiling of 23 Y-STRs in three Brazilian populations
(Forensic Science International: Genetics, 2020) [Artigo]Y-chromosomal STRs are important markers in forensic genetics, due to some peculiar characteristics. The absence of recombination makes them a useful tool to infer kinship in complex cases involving distant paternal ... -
Incorporation of Ursolic Acid in Liquid Crystalline Systems Improves the Antifungal Activity Against Candida Sp
(Journal of Pharmaceutical Innovation, 2020) [Artigo]Purpose: Infectious diseases caused by Candida sp. have high drug resistance due to the uncontrolled use of antibiotics. Among the natural products, ursolic acid (UA), a triterpene, has been increasing interest due to its ... -
Novel bioadhesive polycarbophil-based liquid crystal systems containing Melaleuca alternifolia oil as potential repellents against Aedes aegypti
(Journal of Molecular Liquids, 2020) [Artigo]Dengue, chikungunya, zika, and urban yellow fever are diseases which etiologic agents are transmitted by the bite of Aedes aegypti female mosquitoes, being responsible for serious public health problems. Essential oils, ... -
Shelter dogs as indicators for Trypanosoma cruzi infection in an urban area of Aracaju, Brazil
(Acta Tropica, 2020) [Artigo]Shelters are places that receive certain species of domestic animals, mostly dogs and cats, that are normally abandoned. These animals are easy to handle because they are crowded and have limited movement. Dogs, due to the ... -
Botanical insecticide–based nanosystems for the control of Aedes (Stegomyia) aegypti larvae
(Environmental Science and Pollution Research, 2020) [Resenha]Aedes (Stegomyia) aegypti is a cosmopolitan species that transmits arbovirus of medical importance as dengue, Zika, and chikungunya. The main strategy employed for the control of this mosquito is the use of larvicidal ... -
Biological Properties and Analytical Methods for Micafungin: A Critical Review
(Critical Reviews in Analytical Chemistry, 2020) [Resenha]Micafungin is characterized as one of the most active available drugs for candidemia treatment; however, their use is also associated in prophylaxis protocols in cases of invasive fungal infections. The use of this drug ... -
Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria
(ACS Medicinal Chemistry Letters, 2020) [Artigo]A series of N-phenyl-2,5-dimethylpyrrole derivatives, designed as hybrids of the antitubercular agents BM212 and SQ109, have been synthesized and evaluated against susceptible and drug-resistant mycobacteria strains. ... -
Spirocyclic lactams and curvulinic acid derivatives from the endophytic fungus Curvularia lunata and their antibacterial and antifungal activities
(Fitoterapia, 2020) [Artigo]Curvularia lunata, isolated from the capitula of Paepalanthus chiquitensis (Eriocaulaceae), was cultured in potato dextrose broth (PDB) medium. The ethyl acetate extract yielded two new spirocyclic γ-lactams (3 and 4), and ... -
Silver complexes with fluoroanthranilic acid isomers: Spectroscopic characterization, antimycobacterial activity and cytotoxic studies over a panel of tumor cells
(Inorganica Chimica Acta, 2020) [Artigo]This manuscript presents three silver(I) complexes with fluoroanthranilic acid (fa) isomers, [Ag(4fa)]n, [Ag(5fa)]n and [Ag(6fa)]n, which were named as Ag4fa, Ag5fa and Ag6fa, respectively. The 1:1 metal/ligand molar ... -
Experimental data on novel Fe(III)-complexes containing phenanthroline derivatives for their anticancer properties
(Data in Brief, 2019) [Data paper]This dataset is related to the research article entitled “May iron(III) complexes containing phenanthroline derivatives as ligands be prospective anticancer agents?” [1]. It includes the characterization by UV–Vis absorption ... -
New Silver(I) Coordination Compound Loaded into Polymeric Nanoparticles as a Strategy to Improve in Vitro Anti- Helicobacter pylori Activity
(Molecular Pharmaceutics, 2020) [Artigo]Helicobacter pylori inhabits the gastric epithelium and can promote the development of gastric disorders, such as peptic ulcers, acute and chronic gastritis, mucosal lymphoid tissue (MALT), and gastric adenocarcinomas. To ... -
Genotoxicological safety assessment of puree-only edible films from onion bulb (Allium cepa L.) for use in food packaging-related applications
(Journal of Food Science, 2020) [Artigo]Abstract: The production of films and coatings from onion (Allium cepa L.) to be applied as packaging is attractive, due to its high nutritional and therapeutic value. Also, it can collaborate to minimize environmental ... -
Nanotechnological strategies for systemic microbial infections treatment: A review
(International Journal of Pharmaceutics, 2020) [Resenha]Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug approaches applied for the rapid and necessary treatment contribute to increase the levels of death in affected patients. Several ... -
Nanosystems against candidiasis: a review of studies performed over the last two decades
(Critical Reviews in Microbiology, 2020) [Resenha]The crescent number of cases of candidiasis and the increase in the number of infections developed by non-albicans species and by multi-resistant strains has taken the attention of the scientific community, which has been ... -
Parasite × vector relationship in Chagas disease: does Trypanosoma cruzi (Chagas, 1909) infection affect the spermatogenesis of Triatoma infestans (Klug, 1834)?
(Parasitology Research, 2020) [Artigo]The parasite-vector interaction of Chagas disease is still poorly understood and the understanding of this relationship can help in the development of new strategies to control Trypanosoma cruzi transmission, which is the ... -
Cytotaxonomy of dipetalogaster maxima uhler, 1894 (Hemiptera, reduviidae, triatominae)
(Brazilian Journal of Biology, 2020) [Artigo]The Triatomini tribe consists of ten genera and is regarded as one of the most important tribes from epidemiological point of view. The genus Dipetalogaster Usinger, 1939 is composed only by the species Dipetalogaster ...