RSS 1.0Artigos - Ciências Biológicas - FCFAR
Browse by
Recent Submissions
-
Sulfonamide-containing copper(II) metallonucleases: Correlations with in vitro antimycobacterial and antiproliferative activities
; ; ; Ribeiro, Camila M.
; Pavan, Fernando R. ; ; ; ; (Journal of Inorganic Biochemistry, 2018) [Artigo]
The bis-(1,10-phenanthroline)copper(I) complex, [Cu(I)(phen)2]+, was the first copper-based artificial nuclease reported in the literature. The biological and ligand-like properties of sulfonamides make them good candidates ... -
New heterobimetallic ferrocenyl derivatives: Evaluation of their potential as prospective agents against trypanosomatid parasites and Mycobacterium tuberculosis
; ; ; ; Ribeiro, Camila M.; Pavan, Fernando R. ; (Journal of Inorganic Biochemistry, 2018) [Artigo]
Searching for prospective agents against infectious diseases, four new ferrocenyl derivatives, [M(L)(dppf)4](PF6), with M = Pd(II) or Pt(II), dppf = 1,1′-bis(dipheny1phosphino) ferrocene and HL = tropolone (HTrop) or ... -
Trypanosoma cruzi: analysis of two different strains after piplartine treatment
Vieira, Gabriela Alves Licursi; ; Regasini, Luis Octávio ; Cotinguiba, Fernando ; ; ; Furlan, Maysa ; Cicarelli, Regina Maria Barretto (Brazilian Journal of Infectious Diseases, 2018) [Artigo]
The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas’ disease. This is a serious parasitic disease that occurs in Latin ... -
Effect of electrolytes as adjuvants in GFP and LPS partitioning on aqueous two-phase systems: 1. Polymer-polymer systems
Lopes, André Moreni; ; dos Santos-Ebinuma, Valéria Carvalho ; ; Valentini, Sandro Roberto ; Pereira, Jorge Fernando Brandão (Separation and Purification Technology, 2018) [Artigo]
The production of recombinant biopharmaceuticals is highly dependent of a proper choice of the downstream processing stages. Particularly, the purification that must ensure that all the endotoxins (lipopolysaccharides - ... -
Structure/activity of PtII/N,N-Disubstituted-N’-acylthiourea complexes: Anti-tumor and anti-mycobacterium tuberculosis activities
; ; ; ; ; ; ; ; ; Pavan, Fernando R. et al. (Journal of the Brazilian Chemical Society, 2018) [Artigo]
The syntheses, characterization, cytotoxicity against tumor cells and anti-Mycobacterium tuberculosis activity assays of PtII/PPh3/N,N-disubstituted-N’-acylthioureas complexes with general formulae [Pt(PPh3)2(L)]PF6, PPh3 ... -
Genetic correlates of clarithromycin susceptibility among isolates of the Mycobacterium abscessus group and the potential clinical applicability of a PCR-based analysis of erm(41)
; Pavan, Fernando; Sato, Daisy N. ; Leite, Clarice Q.F. ; ; (Journal of Antimicrobial Chemotherapy, 2018) [Artigo]
Objectives: To define the genetic basis of clarithromycin resistance among isolates of the Mycobacterium abscessus group (MAG). Methods: We analysed 133 isolates identified as MAG. Species identification was confirmed by ... -
Metronidazole-loaded polyethyleneimine and chitosan-based liquid crystalline system for treatment of staphylococcal skin infections
Victorelli, Francesca Damiani; Calixto, Giovana Maria Fioramonti ; Dos Santos Ramos, Matheus Aparecido ; Bauab, Taís Maria ; Chorilli, Marlus (Journal of Biomedical Nanotechnology, 2018) [Artigo]
Staphylococcus aureus is a common gram-positive bacterium of the human skin microbiota. It is also a dangerous pathogen that can cause serious and even lethal skin infections. The topical administration of metronidazole ... -
A Silver Complex with Cycloserine: Synthesis, Spectroscopic Characterization, Crystal Structure and In Vitro Biological Studies
; ; ; Pavan, Fernando Rogério; Ribeiro, Camila Maríngolo ; ; ; ; ; et al. (ChemistrySelect, 2018) [Artigo]
Synthesis, characterization and biological activities of a silver(I) complex with cycloserine (AgCIC) are presented. Elemental, thermal and mass spectrometric analyses permitted proposing the minimal formula AgC3H5N2O2. ... -
Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity
Dos Santos Fernandes, Guilherme Felipe; De Souza, Paula Carolina ; ; ; ; ; ; ; ; et al. (Journal of Medicinal Chemistry, 2017) [Artigo]
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the infectious disease responsible for the highest number of deaths worldwide. Herein, 22 new N-oxide-containing compounds were synthesized followed by in vitro ... -
First record of Lutzomyia (Lutzomyia) longipalpis (Diptera: Psychodidae: Phlebotominae) on the trinational frontier (Brazil-Peru-Bolivia) of South-Western Amazonia
; ; Pinto, Mara Cristina; Galati, Eunice Aparecida Bianchi ; ; (Journal of Medical Entomology, 2017) [Artigo]
In South America, the main sand fly species involved in the transmission of Leishmania infantum chagasi (Cunha & Chagas, 1937), etiological agent of the visceral leishmaniasis (VL), is Lutzomyia longipalpis (Lutz & Neiva, ... -
Avaliação de proteínas fluorescentes por espectrofluorescência tridimensional (3d)
Dos Santos, Nathalia Vieira; Pedrolli, Danielle Biscaro ; Valentini, Sandro Roberto ; Primo, Fernando Lucas ; Pereira, Jorge Fernando Brandão (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017) [Artigo]
-
Estudo do impacto da função de eIF5A em processos celulares envolvendo a mitocôndria
Pinheiro, Anderson Amendola; Barbosa, Natália Moreira ; Valentini, Sandro Roberto ; Zanelli, Cleslei Fernando (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017) [Nota]
-
Avaliação do potencial de novas moléculas para o tratamento da tuberculose
Campos, Débora Leite; ; Souza, Paula Carolina ; Pavan, Fernando Rogério (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017) [Artigo]
-
Criansafe 2017: Atividades interativas sobre educação sexual para adolescentes de uma escola estadual
Pianta, Isabela Mouro; Nogueira, Fabiane Perim ; Dos Santos, Letícia Ferreira ; Wadt, Gabriela ; Furlan, Letícia Cristina ; Assad, Matheus Marques Sanchez ; Marin, Marcelo Tadeu ; Pinto, Mara Cristina (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017) [Artigo]
-
Mutation rates for 20 STR loci in a population from São Paulo state, Southeast, Brazil
Martinez, Juliana; Braganholi, Danilo Faustino ; Ambrósio, Isabela Brunelli ; Polverari, Fernanda Silva ; Cicarelli, Regina Maria Barretto (Annals of Human Biology, 2017) [Artigo]
Short tandem repeats (STRs) are genetic markers largely employed in forensic analysis and paternity investigation cases. When an inconsistency between the parent and child is considered as a possible mutation, the mutation ... -
Breeding protocol for the sand fly Nyssomyia neivai (Diptera: Psychodidae) in laboratory conditions
; da Rocha Silva, Flávia Benini; Machado, Vicente Estevam ; Oliveira, Wanderson Henrique Cruz ; de Castro, Camila Feitosa ; ; Pinto, Mara Cristina (Acta Tropica, 2017) [Artigo]
The information in this protocol covers from the basic steps and material necessary to start a sand fly colony up to the specific details which are important to the success of a Nyssomyia neivai colony. The greatest problems ... -
Palladium(II)/N,N-disubstituted-N′-acylthioureas complexes as anti-Mycobacterium tuberculosis and anti-Trypanosoma cruzi agents
; ; ; ; ; ; ; Pavan, Fernando R.; ; et al. (Polyhedron, 2017) [Artigo]
The new complexes of Pd(II) with N,N-disubstituted-N′-acylthioureas:[(1) [Pd(dppf)(N,N-dimethyl-N′-benzoylthioureato-k2O,S)]PF6, (2) [Pd(dppf)(N,N-diethyl-N′-benzoylthioureato-k2O,S)]PF6, (3) [Pd(dppf)(N,N-dibuthyl-N′-be ... -
Novel copper(II) complexes with hydrazides and heterocyclic bases: Synthesis, structure and biological studies
; ; ; ; Campos, Débora L.; Pavan, Fernando R. ; ; ; ; et al. (Journal of Inorganic Biochemistry, 2017) [Artigo]
Five new copper(II) complexes of the type [Cu(N[sbnd]O)(N[sbnd]N)(ClO4)2], in which N[sbnd]O = 4-fluorophenoxyacetic acid hydrazide (4-FH) or 4-nitrobenzoic hydrazide (4-NH) and N[sbnd]N = 1,10-phenanthroline (phen), ... -
New antimycobacterial agents in the pre-clinical phase or beyond: recent advances in patent literature (2001–2016)
da Silva, Patricia Bento; Campos, Débora Leite ; Ribeiro, Camila Maríngolo ; da Silva, Isabel Cristiane ; Pavan, Fernando Rogério (Expert Opinion on Therapeutic Patents, 2017) [Resenha]
Introduction: Tuberculosis, an infectious disease, has caused more deaths worldwide than any other single infectious disease, killing more than 1.5 million people each year; equating to 4,100 deaths a day. In the past ... -
Solid phase microextraction, sand flies, oviposition pheromones, plaster of Paris and siloxanes—What is in common?
; ; Machado, Vicente Estevam; da Rocha Silva, Flávia Benini ; de Castro, Camila Feitosa ; ; Oliveira, Wanderson Henrique Cruz ; Pinto, Mara Cristina (Acta Tropica, 2017) [Artigo]
Sand flies are natural hosts of various microorganisms. Due to their epidemiological importance, sand fly colonies are kept in laboratories to be studied in terms of their biology and vector/host/parasite interactions. In ...