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dc.contributor.authorTamega, A.De.A. [UNESP]
dc.contributor.authorMiot, L. D B [UNESP]
dc.contributor.authorBonfietti, C. [UNESP]
dc.contributor.authorGige, T. C. [UNESP]
dc.contributor.authorMarques, Mariângela Esther Alencar [UNESP]
dc.contributor.authorMiot, Hélio Amante [UNESP]
dc.date.accessioned2014-05-27T11:28:20Z
dc.date.available2014-05-27T11:28:20Z
dc.date.issued2013-02-01
dc.identifierhttp://dx.doi.org/10.1111/j.1468-3083.2011.04430.x
dc.identifier.citationJournal of the European Academy of Dermatology and Venereology, v. 27, n. 2, p. 151-156, 2013.
dc.identifier.issn0926-9959
dc.identifier.issn1468-3083
dc.identifier.urihttp://hdl.handle.net/11449/74503
dc.description.abstractBackground Melasma is a common acquired chronic hypermelanosis of sun-exposed areas which significantly impacts quality of life. There are few epidemiological studies in medical literature concerning these patients. Objective Characterize clinical and epidemiological data on Brazilian female patients with melasma. Methods A semi-structured questionnaire was administered to melasma patients treated at a dermatology clinic between 2005 and 2010. Association between variables was performed by multivariate regression models. Results We assessed 302 patients; intermediate skin phototypes III (34.4%) and IV (38.4%) were prevalent. Mean disease onset age was 27.5 ± 7.8 years and familiar occurrence of melasma was identified in 56.3%. The most commonly reported trigger factors were pregnancy (36.4%), contraceptive pills (16.2%) and intense sun exposure (27.2%). Preferred facial topographies were zygomatic (83.8%), labial superior (51.3%) and frontal (49.7%). Pregnancy induced melasma has been associated to early disease (OR = 0.86) and number of pregnancies (OR = 1.39). Childbearing was correlated to melasma extension. Older disease onset age was associated to darker skin phototypes. Co-occurrence of facial topographies supported clinical classification as centrofacial and peripheral melasma. Conclusion This population was characterized by: a high prevalence in adult females, intermediate skin phototypes, disease precipitation by hormonal stimulus and familiar genetic influence. © 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.en
dc.format.extent151-156
dc.language.isoeng
dc.relation.ispartofJournal of the European Academy of Dermatology and Venereology
dc.sourceScopus
dc.subjectoral contraceptive agent
dc.subjectadult
dc.subjectchloasma
dc.subjectclinical assessment
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjectquestionnaire
dc.subjectsun exposure
dc.subjectAdult
dc.subjectBrazil
dc.subjectFace
dc.subjectFemale
dc.subjectHumans
dc.subjectHydrocortisone
dc.subjectMelanosis
dc.subjectPregnancy
dc.subjectThyrotropin
dc.subjectYoung Adult
dc.titleClinical patterns and epidemiological characteristics of facial melasma in Brazilian womenen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationDepartment of Dermatology Botucatu Medical School Sao Paulo State University, Botucatu, SP
dc.description.affiliationDepartment of Pathology Botucatu Medical School Sao Paulo State University, Botucatu, SP
dc.description.affiliationUnespDepartment of Dermatology Botucatu Medical School Sao Paulo State University, Botucatu, SP
dc.description.affiliationUnespDepartment of Pathology Botucatu Medical School Sao Paulo State University, Botucatu, SP
dc.identifier.doi10.1111/j.1468-3083.2011.04430.x
dc.identifier.wosWOS:000313883900028
dc.rights.accessRightsAcesso restrito
dc.identifier.scopus2-s2.0-84872688340
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
dc.identifier.lattes2543633050941005
dc.identifier.lattes7528116925519142
unesp.author.lattes2543633050941005
unesp.author.lattes7528116925519142
unesp.author.orcid0000-0002-2596-9294[6]
dc.relation.ispartofjcr4.287
dc.relation.ispartofsjr1,831
dc.relation.ispartofsjr1,831
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