Artigos - Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) - Botucatu
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A biocomplex to repair experimental critical size defects associated with photobiomodulation therapy
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2022) [Artigo]Background: The association of scaffolds to repair extensive bone defects can contribute to their evolution and morphophysiological recomposition. The incorporation of particulate biomaterials into three-dimensional fibrin ... -
A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice
(Journal of Proteomics, 2022) [Artigo]Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and complex pathophysiological condition. Bothrops leucurus is the main species of medical relevance found in the Atlantic coast in the ... -
Variant expression signatures of microRNAs and protein related to growth in a crossbreed between two strains of Nile tilapia (Oreochromis niloticus)
(Genomics, 2021) [Artigo]Nile tilapia (Oreochromis niloticus) is a species of worldwide importance for aquaculture. A crossbred lineage was developed through introgressive backcross breeding techniques and combines the high growth performance of ... -
Phosphodiesterase-5 inhibitor sildenafil attenuates kidney injury induced by Bothrops alternatus snake venom
(Toxicon, 2021) [Artigo]Acute kidney injury pathogenesis in envenoming by snakes is multifactorial and involves immunologic reactions, hemodynamic disturbances, and direct nephrotoxicity. Sildenafil (SFC), a phosphodiesterase 5 inhibitor, has ... -
Crotoxin: A novel allergen to occupational anaphylaxis
(Annals of Allergy, Asthma and Immunology, 2016) [Artigo] -
Influência das fases de anestro e diestro na competência meiótica oocitária de cadelas
(Brazilian Journal of Veterinary Research and Animal Science, 2015) [Artigo]The bitch has reproductive peculiarities that differentiate it from other species. Several experiments have been conducted to establish efficient protocols for maturation; however, the results appear to be unsatisfactory. ... -
Influência da temperatura de transporte de ovários na maturação in vitro de oócitos caninos coletados em diferentes estágios do ciclo estral
(Brazilian Journal of Veterinary Research and Animal Science, 2015) [Artigo]This study evaluated the influence of estrous cycle stage and transport temperature of ovaries on in vitro maturation of canine oocytes. The bitches were categorized into two groups based on stage of estrus cycle: diestrus ... -
Individual venom profiling of Crotalus durissus terrificus specimens from a geographically limited region: Crotamine assessment and captivity evaluation on the biological activities
(Toxicon, 2013) [Artigo]Crotalus durissus terrificus (Cdt) venom major components comprise crotoxin, crotamine, gyroxin and convulxin. Crotamine exerts a myotoxic action, among others, but its expression varies even amid snakes from the same ... -
The first reported case of human tick paralysis in Brazil: A new induction pattern by immature stages
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2012) [Artigo]Tick paralysis (TP) is a rare disease with rapid progression and potential fatal evolution. Immediately after the diagnosis, removal of all ticks from the body of the patient is mandatory. The present study reports for the ... -
Toxinology and Brazil: A close connection
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2012) [Artigo] -
Who communicates with whom?
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2012) [Artigo] -
A new scenario of bioprospecting of Hymenoptera venoms through proteomic approach
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Resenha]Venoms represent a huge and essentially unexplored reservoir of bioactive components that may cure diseases that do not respond to currently available therapies. This review select advances reported in the literature from ... -
Ovine leptospirosis in Brazil
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Artigo]Leptospirosis is a zoonosis distributed worldwide, endemic mainly in humid subtropical and tropical countries, with epidemic potential. It affects a range of both wild and domestic animals, including sheep, which transport ... -
How to overcome the gap between basic research and clinical trials?
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Editorial] -
Treatment of venous ulcers with fibrin sealant derived from snake venom
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Artigo]Venous ulcers of the lower limbs complicated by infection or chronicity represent a serious public health problem. The elevated number of those afflicted burdens the health services, interferes in quality of life and causes ... -
Triple bothropic envenomation in horses caused by a single snake
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Artigo]In the present study, snakebites caused by a single Bothrops pauloensis simultaneously affecting three male adult horses are described. Whereas the first two affected horses were six years old, the third was 16 years old; ... -
Universities and neglected diseases - It is not enough to have the knowledge, it must be applied
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Editorial] -
Biochemical and biological evaluation of gyroxin isolated from Crotalus durissus terrificus venom
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011) [Artigo]Gyroxin, a thrombin-like enzyme isolated from Crotalus durissus terrificus venom and capable of converting fibrinogen into fibrin, presents coagulant and neurotoxic activities. The aim of the present study was to evaluate ... -
Purification, characterization, crystallization and theoretical molecular modeling of gyroxin fraction from Crotalus durissus terrificus venom (Laurenti, 1768)
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2010) [Artigo]The venom of Crotalus durissus terrificus snakes presents various substances, including a serine protease with thrombin-like activity, called gyroxin, that clots plasmatic fibrinogen and promote the fibrin formation. The ... -
Envenomation caused by Latrodectus geometricus in São Paulo State, Brazil: A case report
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2009) [Artigo]Widow spiders (Latrodectus spp.), also known as black widows, have a worldwide distribution and can cause latrodectism. To the best of our knowledge, in Brazil, only one case of Latrodectus geometricus (Koch, 1841) ...