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dc.contributor.authorBagliotti Meneguin, Andréia [UNESP]
dc.contributor.authorCury, Beatriz Stringhetti Ferreira [UNESP]
dc.contributor.authorEvangelista, Raul Cesar [UNESP]
dc.date.accessioned2014-05-27T11:30:53Z
dc.date.available2014-05-27T11:30:53Z
dc.date.issued2014-01-01
dc.identifierhttp://dx.doi.org/10.1016/j.carbpol.2013.07.077
dc.identifier.citationCarbohydrate Polymers, v. 99, p. 140-149.
dc.identifier.issn0144-8617
dc.identifier.urihttp://hdl.handle.net/11449/76927
dc.description.abstractFree films were obtained by the solvent casting method from retrograded starch-pectin dispersions at different polymer proportions and concentrations with and without plasticizer. Film forming dispersions were characterized according to their hardness, birefringence and rheological properties. The polymer dispersions showed a predominantly viscous behavior (G″ > G′) and the absence of plasticizers lead to building of stronger structures, while the occurrence of Maltese crosses in the retrograded dispersions indicates the occurrence of a crystalline organization. Analyses of the films included mechanical properties, thickness, superficial and cross sectional morphology, water vapor permeability, liquid uptake ability, X-ray diffractometry, in vitro dissolution and enzymatic digestion. The high resistant starch content (65.8-96.8%) assured the resistance of materials against enzymatic digestion by pancreatin. Changes in the X-ray diffraction patterns indicated a more organized and crystalline structure of free films in relation to isolated polymers. Increasing of pectin proportion and pH values favored the dissolution and liquid uptake of films. Films prepared with lower polymer concentration presented better barrier function (WVP and mechanical properties). © 2013 Elsevier Ltd. All rights reserved.en
dc.format.extent140-149
dc.language.isoeng
dc.relation.ispartofCarbohydrate Polymers
dc.sourceScopus
dc.subjectDissolution
dc.subjectEnzymatic digestion
dc.subjectFree film
dc.subjectPectin X-ray diffraction
dc.subjectResistant starch
dc.subjectCross-sectional morphology
dc.subjectCrystalline organization
dc.subjectEnzymatic digestions
dc.subjectFree films
dc.subjectPolymer concentrations
dc.subjectSolvent casting method
dc.subjectWater vapor permeability
dc.subjectDispersions
dc.subjectDrug delivery
dc.subjectLiquids
dc.subjectMechanical properties
dc.subjectPlasticizers
dc.subjectPolymers
dc.subjectReinforced plastics
dc.subjectSolvents
dc.subjectStarch
dc.subjectX ray diffraction
dc.subjectX ray diffraction analysis
dc.subjectPolymer films
dc.subjectLychnis chalcedonica
dc.titleFilms from resistant starch-pectin dispersions intended for colonic drug deliveryen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationGraduate Program in Pharmaceutical Sciences Faculty of Pharmaceutical Sciences São Paulo State University-UNESP, km 1 Araraquara-Jaú Road, Araraquara, SP
dc.description.affiliationDepartment of Drugs and Pharmaceuticals Faculty of Pharmaceutical Sciences São Paulo State University-UNESP, km 1 Araraquara-Jaú Road, Araraquara, SP
dc.description.affiliationUnespGraduate Program in Pharmaceutical Sciences Faculty of Pharmaceutical Sciences São Paulo State University-UNESP, km 1 Araraquara-Jaú Road, Araraquara, SP
dc.description.affiliationUnespDepartment of Drugs and Pharmaceuticals Faculty of Pharmaceutical Sciences São Paulo State University-UNESP, km 1 Araraquara-Jaú Road, Araraquara, SP
dc.identifier.doi10.1016/j.carbpol.2013.07.077
dc.identifier.wosWOS:000329256600018
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-84883638773
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
dc.identifier.file2-s2.0-84883638773.pdf
dc.identifier.lattes5361569184579557
unesp.author.lattes5361569184579557
unesp.author.orcid0000-0003-3020-9238[2]
dc.relation.ispartofjcr5.158
dc.relation.ispartofsjr1,428
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