Now showing items 1-10 of 320
Involvement of dopamine receptors in diethylpropion-induced conditioning place preference
(Brazilian Journal of Medical and Biological Research, 1998-04-01) [Artigo]
Diethylpropion (DEP) is an amphetamine-like agent used as an anorectic drug. Abuse of DEP has been reported and some restrictions of its use have been recently imposed. The conditioning place preference (CPP) paradigm was ...
Chemopreventive activity of compounds extracted from Casearia sylvestris (Salicaceae) Sw against DNA damage induced by particulate matter emitted by sugarcane burning near Araraquara, Brazil
(Toxicology and Applied Pharmacology, 2012-12-15) [Artigo]
Ethanolic extract of Casearia sylvestris is thought to be antimutagenic. In this study, we attempted to determine whether this extract and casearin X (a clerodane diterpene from C. sylvestris) are protective against the ...
Influence of the single or combined administration of cocaine and testosterone in autonomic and neuroendocrine responses to acute restraint stress
(Journal of Psychopharmacology, 2012-10-01) [Artigo]
Abuse of cocaine and androgenic-anabolic steroids (AASs) has become a serious public health problem. Despite reports of an increase in the incidence of simultaneous abuse of these substances, potential toxic interactions ...
Macrophage activation by Paepalanthus spp. extracts
(Revista Brasileira de Farmacognosia, 2000-01-01) [Artigo]
Macrófagos são conhecidos por exercerem uma importante função de mecanismo de defesa quando estas células são estimuladas com produtos naturais e produtos bacterianos (dentre outros). Uma variedade de citocinas e compostos ...
Effect of the Single or Combined Administration of Cocaine and Testosterone on Cardiovascular Function and Baroreflex Activity in Unanesthetized Rats
(Journal of Cardiovascular Pharmacology, 2012-03-01) [Artigo]
Abuse of cocaine and androgenic-anabolic steroids has become a serious public health problem. Despite reports of an increase in the incidence of simultaneous illicit use of these substances, potential toxic interactions ...
Antimicrobial activity of Piper arboreum and Piper tuberculatum (Piperaceae) against opportunistic yeasts
(African Journal of Biotechnology, 2009-06-17) [Artigo]
In the scope of our ongoing research on bioactive agents from natural sources, 24 extracts and fractions obtained from Piper arboreum Aub. and Piper tuberculatum Jacq. ( Piperaceae) were screened for antifungal activity ...
Phylogenetic and antimicrobial resistance gene analysis of Salmonella Typhimurium strains isolated in Brazil by whole genome sequencing
(PLoS ONE, 2018-08-01) [Artigo]
Whole genome sequencing (WGS) has been used as a powerful technology for molecular epidemiology, surveillance, identification of species and serotype, identification of the sources of outbreaks, among other purposes. In ...
Cytotoxicity of doxorubicin-loaded PLGA and PLGA-PEI nanoparticles: relevance for anti-tumor effects and cardiotoxicity
(European Journal Of Clinical Investigation, 2018-06-01) [Resumo]
Context-specific modulation of cocaine-induced locomotor sensitization and ERK and CREB phosphorylation in the rat nucleus accumbens
(European Journal of Neuroscience, 2009-11-01) [Artigo]
Learned associations are hypothesized to develop between drug effects and contextual stimuli during repeated drug administration to produce context-specific sensitization that is expressed only in the drug-associated ...
Antidiabetic activity of Musa x paradisiaca extracts in streptozotocin-induced diabetic rats and chemical characterization by HPLC-DAD-MS
(Journal Of Ethnopharmacology, 2020-05-23) [Artigo]
Ethnopharmacological relevance: The Musa x paradisiaca L. inflorescence, known as banana blossom or banana heart, is used in traditional medicine for the treatment of diabetes mellitus. Aim of the study: The aim of the ...