Now showing items 1-5 of 5
Ontogênese, estresse e dependência de substâncias psicoativas
(Revista Brasileira de Ciências Farmacêuticas, 2007-09-01) [Artigo]
O estudo da dependência de substâncias psicoativas apresentou grandes avanços conceituais nas últimas décadas. A evolução dos conceitos foi paralela às evidências científicas que têm revelado os aspectos comportamentais e ...
Stress Abolishes the Effect of Previous Chronic Ethanol Consumption on Drug Place Preference and on the Mesocorticolimbic Brain Pathway
(Alcoholism: Clinical and Experimental Research, 2014-05-01) [Artigo]
BackgroundConditioned place preference (CPP) to ethanol (EtOH) is an important addiction-related alteration thought to be mediated by changed neurotransmission in the mesocorticolimbic brain pathway. Stress is a factor of ...
Role of the bed nucleus of the stria terminalis in cardiovascular changes following chronic treatment with cocaine and testosterone: A role beyond drug seeking in addiction?
(Neuroscience, 2013-12-03) [Artigo]
Neural plasticity has been observed in the bed nucleus of the stria terminalis (BNST) following exposure to both cocaine and androgenic-anabolic steroids. Here we investigated the involvement of the BNST on changes in ...
Social defeat stress in rats: escalation of cocaine and speedball binge self-administration, but not heroin
(Psychopharmacology, 2011-05-01) [Artigo]
Exposure to intermittent episodes of social defeat stress can increase drug seeking and leads to intense drug taking in rats.This study investigated the consequences of repeated, intermittent social defeat stress on patterns ...
Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking
(Journal Of Neuroscience, 2015-04-15) [Artigo]
Alcohol and nicotine are the two most co-abused drugs in the world. Previous studies have shown that nicotine can increase alcohol drinking in nondependent rats, yet it is unknown whether nicotine facilitates the transition ...