Now showing items 1-6 of 6
Stress Abolishes the Effect of Previous Chronic Ethanol Consumption on Drug Place Preference and on the Mesocorticolimbic Brain Pathway
(Alcoholism: Clinical and Experimental Research, 2014-05-01) [Artigo]
BackgroundConditioned place preference (CPP) to ethanol (EtOH) is an important addiction-related alteration thought to be mediated by changed neurotransmission in the mesocorticolimbic brain pathway. Stress is a factor of ...
Stress-induced cross-sensitization to amphetamine is related to changes in the dopaminergic system
(Journal of Neural Transmission, 2012-04-01) [Artigo]
Repeated stress engenders behavioral sensitization. The mesolimbic dopamine system is critically involved in drug-induced behavioral sensitization. In the present study we examined the differences between adolescent and ...
Stress-induced reinstatement of amphetamine-conditioned place preference and changes in tyrosine hydroxylase in the nucleus accumbens in adolescent rats
(Pharmacology Biochemistry and Behavior, 2010-08-01) [Artigo]
Drug abuse among humans often begins during adolescence. Exposure to psychostimulants during this age period may have long-term consequences which can render the organism more susceptible to drug abuse and relapse later ...
Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens
(Pharmacology Biochemistry and Behavior, 2012-05-01) [Artigo]
Experimental evidence shows that exposure to stress engenders behavioral sensitization and increases drug-seeking and leads to intense drug taking. However the molecular mechanisms involved in these processes is not well ...
Ontogênese, estresse e dependência de substâncias psicoativas
(Revista Brasileira de Ciências Farmacêuticas, 2007-09-01) [Artigo]
O estudo da dependência de substâncias psicoativas apresentou grandes avanços conceituais nas últimas décadas. A evolução dos conceitos foi paralela às evidências científicas que têm revelado os aspectos comportamentais e ...
Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats
(Brazilian Journal of Medical and Biological Research, 2012-01-01) [Artigo]
Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral ...