Now showing items 1-6 of 6
Envolvimento do sistema dopaminérgico na sensibilização comportamental ao femproporex
(Revista de Ciencias Farmaceuticas, 2002-12-01) [Artigo]
The effects of repeated administration of fenproporex (FEN) on motor activity of rats were studied. FEN-treated group (5.0 mg/kg, i.p., single dose, 7 consecutive days), showed a marked increase in the motor activity of ...
Exposure to acute restraint stress reinstates nicotine-induced place preference in rats
(Behavioural Pharmacology, 2009-02-01) [Artigo]
Tobacco addiction is associated with high rates of relapse to drug use even after prolonged periods of abstinence. Relapse can occur upon reexposure to the drug of abuse, exposure to stress or to stimuli associated with ...
Effect of chronic treatment with Clomipramine on food intake, macronutrient selection and body weight gain in rats
(Biological & Pharmaceutical Bulletin, 2007-08-01) [Artigo]
Long-term treatment with clomipramine (CMI), a tricyclic antidepressant, induces food craving and body weight gain in patients. The present study investigated the effects of chronic treatment with CMI on total food intake, ...
Effects of chronic stress on nicotine-induced locomotor activity and corticosterone release in adult and adolescent rats
(Addiction Biology, 2008-03-01) [Artigo]
We examined nicotine-induced locomotion and increase in corticosterone plasma levels in adolescent and adult animals exposed to chronic restraint stress. Adolescent [postnatal day (P) 28-37] and adult (P60-67) rats were ...
Differential behavioral and neuroendocrine effects of repeated nicotine in adolescent and adult rats
(Pharmacology Biochemistry and Behavior, 2005-03-01) [Artigo]
Despite the high prevalence of tobacco abuse among adolescents, the neurobiology of nicotine addiction has been studied mainly in adult animals. Repeated administration of this drug to adult rats induces behavioral ...
Chronic restraint or variable stresses differently affect the behavior, corticosterone secretion and body weight in rats
(Physiology & Behavior, 2007-01-30) [Artigo]
Organisms are constantly subjected to stressful stimuli that affect numerous physiological processes and activate the hypothalamo-pituitary-adrenal (HPA) axis, increasing the release of glucocorticoids. Exposure to chronic ...