Now showing items 1-10 of 39
Leishmanicidal Activities of Novel Synthetic Furoxan and Benzofuroxan Derivatives
(Antimicrobial Agents and Chemotherapy, 2014-08-01) [Artigo]
A novel series of furoxan (1,2,5-oxadiazole 2-oxide) (compounds 3, 4a and -b, 13a and -b, and 14a to -f) and benzofuroxan (benzo[c][1,2,5] oxadiazole 1-oxide) (compounds 7 and 8a to -c) derivatives were synthesized, ...
Diazepam influences urinary bioindicator of occupational toluene exposure
(Environmental Toxicology And Pharmacology, 2016-12-01) [Artigo]
In the present study, we investigated the influence of diazepam (DZP) on the excretion of TOL by examining their urinary metabolites, hippuric acid (HA) and ortho-cresol (o-C). Male Wistar rats were exposed to TOL (20 ppm) ...
Cytotoxicity of doxorubicin-loaded PLGA and PLGA-PEI nanoparticles: relevance for anti-tumor effects and cardiotoxicity
(European Journal Of Clinical Investigation, 2018-06-01) [Resumo]
rastreamento histoquímico, fitoquímico e biológico de folhas de Plinia cauliflora (DC.) Kausel (Myrtaceae)
(Brazilian Journal of Pharmacognosy, 2010-01-01) [Artigo]
In this work, chemical and biological activities of crude extracts obtained with 50% ethanol, 70% ethanol, acetone:water (7:3; v/v) and chloroform of Plinia cauliflora (DC.) Kausel, Myrtaceae, leaves, a native tree from ...
Biocompatible Microemulsion Modifies the Tissue Distribution of Doxorubicin
(Journal Of Pharmaceutical Sciences, 2014-10-01) [Artigo]
The incorporation of doxorubicin (DOX) in a microemulsion (DOX-ME) has shown beneficial consequences by reducing the cardiotoxic effects of DOX. The aim of this study was to determine the distribution of DOX-ME in Ehrlich ...
Validação de método bioanalítico por HPLC para a determinação do ácido ursólico em plasma
(Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017-01-01) [Nota]
Both alpha(1)- and beta(1)-adrenoceptors in the bed nucleus of the stria terminalis are involved in the expression of conditioned contextual fear
(British Journal of Pharmacology, 2012-09-01) [Artigo]
BACKGROUND and PURPOSE The bed nucleus of the stria terminalis (BNST) is a limbic structure that is involved in the expression of conditioned contextual fear. Among the numerous neural inputs to the BNST, noradrenergic ...
Lateral septal area alpha(1)-and alpha(2)-adrenoceptors differently modulate baroreflex activity in unanaesthetized rats
(Experimental Physiology, 2012-09-01) [Artigo]
The lateral septal area (LSA) is a limbic structure involved in autonomic, neuroendocrine and behavioural responses. An inhibitory influence of the LSA on baroreflex activity has been reported; however, the local ...
Safety Assessment of Potentially Inappropriate Medications (PIM) use in Older People and the Factors Associated with Hospital Admission
(Journal of Pharmacy and Pharmaceutical Sciences, 2011-01-01) [Artigo]
Purpose: Potentially Inappropriate Medications (PIM) use in elderly people may be responsible for the development of Adverse Drug Reaction (ADR) which, when severe, leads to hospital admissions. Objectives: to estimate the ...
Infecções parasitárias na gravidez: prevalência e auto medicação com plantas medicinais na região de Araraquara -São Paulo - Brasil
(Raízes e Rumos, 2014) [Artigo]
Pregnant women are individuals own characteristics, metabolic, endocrinological and immunological transient patterns and require special care. To estimate the prevalence of intestinal parasites in pregnant women and use ...