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New PPAR alpha/gamma/delta Optimal Activator Rationally Designed by Computational Methods
(Journal Of The Brazilian Chemical Society, 2016-09-01) [Artigo]
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that acts as a transcription factor, regulating glucose, lipid and inflammation signaling and it is exploited in type 2 diabetes ...
Essential Oil of Cymbopogon nardus (L.) Rendle: A Strategy to Combat Fungal Infections Caused by Candida Species
(International Journal Of Molecular Sciences, 2016-08-01) [Resenha]
Background: The incidence of fungal infections, especially those caused by Candida yeasts, has increased over the last two decades. However, the indicated therapy for fungal control has limitations. Hence, medicinal plants ...
Pharmacokinetic properties, in vitro metabolism and plasma protein binding of govaniadine an alkaloid isolated from Corydalis govaniana Wall
(Journal Of Pharmaceutical And Biomedical Analysis, 2016-11-30) [Artigo]
Govaniadine (GOV) is an alkaloid isolated from Corydalis govaniana Wall. It has been reported to show a different number of biological activities including anti-urease, leishmanicidal and antinociceptive. The present study ...