Intra-amygdala infusion of midazolam, a benzodiazepine receptor agonist, produces anxiolytic-like effects in mice when first exposed to the elevated plus-maze (EPM) and blocks antinociception induced in mice confined in ...

Threatening situations (e.g., exposure to an elevated plus-maze with four open arms - oEPM) induce behavioral and neurovegetative responses generally accompanied by antinociception animals. The midbrain periaqueductal gray ...