Now showing items 1-4 of 4
Cocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells
(Molecular Brain, 2009-01-01) [Artigo]
Cocaine is a worldwide used drug and its abuse is associated with physical, psychiatric and social problems. The mechanism by which cocaine causes neurological damage is very complex and involves several neurotransmitter ...
Maternal separation stress in male mice: long-term increases in alcohol intake
(Psychopharmacology, 2008-12-01) [Artigo]
In rodents, prolonged maternal separation has been used as a model of developmentally early environmental stress to influence adult drug intake.The aim of the present study was to evaluate the long-term effects of prolonged ...
Amphetamine- and nicotine-induced cross-sensitization in adolescent rats persists until adulthood
(Addiction Biology, 2009-07-01) [Artigo]
Nicotine and psychostimulants are often abused in combination and drug abuse often begins during adolescence and can have long-term consequences. Behavioral sensitization has been suggested as an animal model of neuroplasticity ...
Context-specific modulation of cocaine-induced locomotor sensitization and ERK and CREB phosphorylation in the rat nucleus accumbens
(European Journal of Neuroscience, 2009-11-01) [Artigo]
Learned associations are hypothesized to develop between drug effects and contextual stimuli during repeated drug administration to produce context-specific sensitization that is expressed only in the drug-associated ...