Now showing items 1-6 of 6
The triad indole-3-acetic acid ethyl ester/esterase/horseradish peroxidase as a new cytotoxic prodrug/enzyme combination
(Applied Cancer Research, 2010) [Artigo]
The antibody-directed enzyme prodrug therapy (ADEPT) is a means of restricting the action of toxic drugs to the tumor site. The enzyme/prodrug pair horseradish peroxidase (HRP)/indole-3-acetic acid (IAA) has been studied ...
Serum myeloperoxidase level is Increased in heavy smokers
(Open Journal of Clinical Diagnostics, 2013) [Artigo]
Raised myeloperoxidase (MPO) serum levels are associated with endothelial dysfunction and cigarette smoking is a risk factor for cardiovascular diseases. Since myocardial infarction is associated with leukocytosis and ...
Caffeic Acid Phenethyl Ester: Consequences of Its Hydrophobicity in the Oxidative Functions and Cytokine Release by Leukocytes
(Evidence-based Complementary And Alternative Medicine, 2014-01-01) [Artigo]
Numerous anti-inflammatory properties have been attributed to caffeic acid phenethyl ester (CAPE), an active component of propolis. NADPH oxidases are multienzymatic complexes involved in many inflammatory diseases. Here, ...
Inhibitory effect of gallic acid and its esters on 2,2'-azobis(2-amidinopropane)hodrpchloride (AAPH)-induced hemolysis and depletion of intracellular glutathione in erythrocytes
(Journal of Agricultural and Food Chemistry, 2010) [Artigo]
The protective effect of gallic acid and its esters, methyl, propyl, and lauryl gallate, against 2,2'-azobis(2-amidinopropane)hydrochloride (AAPH)-induced hemolysis and depletion of intracellular glutathione (GSH) in ...
Recombinant hepatitis C virus-envelope protein 2 interactions with low-density lipoprotein/CD81 receptors
(Memorias do Instituto Oswaldo Cruz, 2015-06-01) [Artigo]
Hepatitis C virus (HCV) envelope protein 2 (E2) is involved in viral binding to host cells. The aim of this work was to produce recombinant E2B and E2Y HCV proteins in Escherichia coli and Pichia pastoris, respectively, ...
Hydrophobicity and antioxidant activity acting together for the beneficial health properties of nordihydroguaiaretic acid
(Food &function, 2015-01-01) [Artigo]
Nordihydroguaiaretic acid (NDGA) and rosmarinic acid (RA), phenolic compounds found in various plants and functional foods, have known antioxidant and anti-inflammatory properties. In the present study, we comparatively ...