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Ximenes, Valdecir Farias [UNESP] (22)
Fonseca, Luiz Marcos da [UNESP] (6)Brunetti, Iguatemy Lourenço [UNESP] (5)... View MoreDate Issued2015 (2)2014 (2)2013 (3)2012 (3)2010 (4)2008 (1)2007 (6)2006 (1)Language
eng (22)
SponsorFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) (10)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) (9)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (4)SubjectHypochlorous acid (4)horseradish peroxidase (3)apocynin (2)... View MoreTypeArtigo (22)Campus
Universidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquara (22)
Universidade Estadual Paulista (UNESP), Faculdade de Ciências, Bauru (20)Universidade Estadual Paulista (UNESP), Instituto de Química, Araraquara (4)

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Artigo

The triad indole-3-acetic acid ethyl ester/esterase/horseradish peroxidase as a new cytotoxic prodrug/enzyme combination 

Pereira, Débora Helena [UNESP]; Kitagawa, Rodrigo Rezende [UNESP]; Raddi, Maria Stella Gonçalves [UNESP]; Fonseca, Luiz Marcos da [UNESP]; Ximenes, Valdecir Farias [UNESP] (Applied Cancer Research, 2010) [Artigo]
The antibody-directed enzyme prodrug therapy (ADEPT) is a means of restricting the action of toxic drugs to the tumor site. The enzyme/prodrug pair horseradish peroxidase (HRP)/indole-3-acetic acid (IAA) has been studied ...
item
Artigo

Serum myeloperoxidase level is Increased in heavy smokers 

Martins, Anfrá B. [UNESP]; Ximenes, Valdecir Farias [UNESP]; Fonseca, Luiz Marcos da [UNESP] (Open Journal of Clinical Diagnostics, 2013) [Artigo]
Raised myeloperoxidase (MPO) serum levels are associated with endothelial dysfunction and cigarette smoking is a risk factor for cardiovascular diseases. Since myocardial infarction is associated with leukocytosis and ...
item
Artigo

Alkyl caffeates as anti-helicobacter pylori and scavenger of oxidants produced by neutrophils 

Paracatu, Luana Chiquetto [UNESP]; Bonacorsi, Cibele [UNESP]; De Farias, Carolina Maria Quinello Gomes [UNESP]; Nazaré, Ana Carolina [UNESP]; Petrônio, Maicon Segalla [UNESP]; Regasini, Luiz Octávio [UNESP]; Siqueira Silva, Dulce Helena [UNESP]; Raddi, Maria Stella Gonçalves [UNESP]; Da Fonseca, Luiz Marcos [UNESP]; Ximenes, Valdecir Farias [UNESP] (Medicinal Chemistry, 2014-02-01) [Artigo]
Helicobacter pylori pathogenic action involves the colonization of the gastrointestinal tract and a large production of reactive oxygen species (ROS) by the neutrophils attracted to the site of infection. The aim of this ...
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Artigo

Caffeic Acid Phenethyl Ester: Consequences of Its Hydrophobicity in the Oxidative Functions and Cytokine Release by Leukocytes 

Paracatu, Luana Chiquetto [UNESP]; Quinello Gomes Faria, Carolina Maria [UNESP]; Quinello, Camila; Renno, Camila; Palmeira, Patricia; Zeraik, Maria Luiza [UNESP]; Fonseca, Luiz Marcos da [UNESP]; Ximenes, Valdecir Farias [UNESP] (Evidence-based Complementary And Alternative Medicine, 2014-01-01) [Artigo]
Numerous anti-inflammatory properties have been attributed to caffeic acid phenethyl ester (CAPE), an active component of propolis. NADPH oxidases are multienzymatic complexes involved in many inflammatory diseases. Here, ...
item
Artigo

Effects of oxidation of lysozyme by hypohalous acids and haloamines on enzymatic activity and aggregation 

Petronio, Maicon S.; Ximenes, Valdecir Farias [UNESP] (Biochimica et Biophysica Acta: Proteins and Proteomics, 2012-10-01) [Artigo]
Hen egg white lysozyme (HEL), an antibacterial enzyme, is a prototype protein for studying the physical and chemical events that underlie the formation of amyloid fibril aggregates. Here, we studied alterations in enzymatic ...
item
Artigo

The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N-1-acetyl-N (2)-formyl-5-methoxykynuramine 

Ximenes, Valdecir Farias [UNESP]; Rodrigues, Ana Paula [UNESP]; Cabello, Claudio [UNESP]; Menezes, Manoel Lima de [UNESP]; Fernandes, João Roberto [UNESP] (Journal of Pineal Research, 2008-03-01) [Artigo]
Accumulating evidence points to relationships between increased production of reactive oxygen or decreased antioxidant protection in schizophrenic patients. Chlorpromazine (CPZ), which remains a benchmark treatment for ...
item
Artigo

Inhibition of Lysozyme by Taurine Dibromamine 

Petronio, M. S. [UNESP]; Ximenes, Valdecir Farias [UNESP] (Protein and Peptide Letters, 2013-11-01) [Artigo]
Hypobromous acid (HOBr) is a powerful oxidant produced by stimulated neutrophils and eosinophils. Taurine, a non-protein amino acid present in high amounts in the leukocytes, reacts instantaneously with HOBr leading to ...
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Artigo

Investigation of Human Albumin-Induced Circular Dichroism in Dansylglycine 

Graciani, Fernanda S. [UNESP]; Ximenes, Valdecir Farias [UNESP] (PLOS ONE, 2013-10-16) [Artigo]
Induced circular dichroism (ICD), or induced chirality, is a phenomenon caused by the fixation of an achiral substance inside a chiral microenvironment, such as the hydrophobic cavities in proteins. Dansylglycine belongs ...
item
Artigo

Chemiluminescent determination of leukocyte alkaline phosphatase: An advantageous alternative to the cytochemical assay 

Kanegae, Marilia P. P.; Ximenes, Valdecir Farias [UNESP]; Falcao, Roberto P.; Colturato, Virgilio A. R.; de Mattos, Ederson R.; Brunetti, Iguatemy Lourenço [UNESP]; Marcos da Fonseca, Luiz (Journal of Clinical Laboratory Analysis, 2007-01-01) [Artigo]
The determination of leukocyte alkaline phosphatasd (LAP) is used as an aid to diagnose many diseases in the laboratory. For example, it can be used to distinguish chronic myeloid leukemia (CML) from other myeloproliferative ...
item
Artigo

Oxidation of acetylacetone catalyzed by horseradish peroxidase in the absence of hydrogen peroxide 

Rodrigues, Ana Paula; da Fonseca, Luiz Marcos; de Faria Oliveira, Olga M.; Brunetti, Iguatemy Lourenço [UNESP]; Ximenes, Valdecir Farias [UNESP] (Biochimica et Biophysica Acta: General Subjects, 2006-12-01) [Artigo]
Horseradish peroxidase (HRP) is a plant enzyme widely used in biotechnology, including antibody-directed enzyme prodrug therapy (ADEPT). Here, we showed that HRP is able to catalyze the autoxidation of acetylacetone in the ...
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Universidade Estadual Paulista "Júlio de Mesquita Filho"
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Universidade Estadual Paulista 'Júlio de Mesquita Filho'
 

 


Universidade Estadual Paulista "Júlio de Mesquita Filho"
About Repositório Institucional UNESP • Frequently Asked Questions (FAQ) • Contact Us
Universidade Estadual Paulista 'Júlio de Mesquita Filho'