Razão triglicérides/HDL-C e proteína C reativa de alta sensibilidade na avaliação do risco cardiovascular

Página do item simplificado
dc.contributor.authorVieira, Eder Andrade
dc.contributor.authorCarvalho, Wilson Andrade [UNESP]
dc.contributor.authorJúnior, Roque Aras
dc.contributor.authorCouto, Fábio David
dc.contributor.authorCouto, Ricardo David
dc.contributor.institutionCurso de Especializacao em Topicos Avancados em Diagnostico Laboratorial
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.contributor.institutionHumana Pela Fundação Oswaldo Cruz/Bahia (FIOCRUZ/BA)
dc.contributor.institutionUniversidade Federal do Recôncavo da Bahia (UFRB)
dc.contributor.institutionFIOCRUZ/BA
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionLaboratório de Bioquímica Clínica
dc.date.accessioned2014-05-27T11:25:50Z
dc.date.available2014-05-27T11:25:50Z
dc.date.issued2011-04-01
dc.description.abstractIntroduction: Calculated indexes from laboratory measurements and the determination of plasma markers are commonly used in cardiovascular risk assessment. Objective: To use triglycerides/high-density lipoprotein cholesterol (HDL-C) ratio, estimate of low-density lipoprotein (LDL) particle size and high sensitive C-reactive protein (hs-CRP) levels to the clinical and laboratorial assessment of coronary risk among patients with coronary disease. Material and methods: Sixty patients were chosen accordingly, 36 female (F) (65 ± 9 years of age) and 24 male (M) (55 ± 10 years of age) diagnosed with stable ischemic cardiopathy at Ana Neri Hospital, Salvador, Bahia, Brazil. The investigation was carried out at the Clinical Biochemistry Laboratory of the College of Pharmacy at Federal University of Bahia (UFBA). Blood samples were collected after a 12-hour fast to determine hs-CRP, lipid profile and risk indicators. All data were assessed through Syncron LX®20 Beckman Coulter. The inferential analysis results were considered significant when p ≤ 5%. Data analysis was carried out with GraphPad Prism® (4.03 version) software. Results: Data analysis showed a positive correlation between hs-CRP and triglycerides/HDL-C ratio only among women (r = 0.4; p = 0.0442), n = 36. The analysis of other parameters did not show any significance. Conclusion: The triglycerides/HDL-C ratio and hs-CRP may be used as indicators of increase in cardiovascular risk among women with coronary artery disease (CAD).en
dc.description.affiliationCurso de Especializacao em Topicos Avancados em Diagnostico Laboratorial
dc.description.affiliationUniversidade Estadual Paulista (UNESP)
dc.description.affiliationDepartamento de Análises Clínicas e Toxicológicas Faculdade de Farmácia UFBA
dc.description.affiliationMedicina e Saúde UFBA
dc.description.affiliationDepartamento de Medicina Faculdade de Medicina UFBA
dc.description.affiliationHumana Pela Fundação Oswaldo Cruz/Bahia (FIOCRUZ/BA)
dc.description.affiliationBiologia Molecular e Genética Centro de Ciencias Agrarias, Ambientais e Biologicas da Universidade Federal Do Reconcavo da Bahia
dc.description.affiliationLipídios, Lipoproteínas e Aterosclerose FIOCRUZ/BA
dc.description.affiliationUniversidade de São Paulo (USP)
dc.description.affiliationDepartamento de Análises Clínicas e Toxicológicas Laboratório de Bioquímica Clínica Campus Universitário de Ondina, Rua Barão de Geremoabo, s/n, Salvador-BA, CEP: 40170-115
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP)
dc.format.extent113-118
dc.identifierhttp://dx.doi.org/10.1590/S1676-24442011000200004
dc.identifier.citationJornal Brasileiro de Patologia e Medicina Laboratorial, v. 47, n. 2, p. 113-118, 2011.
dc.identifier.doi10.1590/S1676-24442011000200004
dc.identifier.file2-s2.0-79958058426.pdf
dc.identifier.issn1676-2444
dc.identifier.issn1678-4774
dc.identifier.scieloS1676-24442011000200004
dc.identifier.scopus2-s2.0-79958058426
dc.identifier.urihttp://hdl.handle.net/11449/72358
dc.language.isopor
dc.relation.ispartofJornal Brasileiro de Patologia e Medicina Laboratorial
dc.relation.ispartofsjr0,143
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCoronary artery disease
dc.subjectRisk estimates
dc.subjectSensible C-reactive protein
dc.titleRazão triglicérides/HDL-C e proteína C reativa de alta sensibilidade na avaliação do risco cardiovascularpt
dc.title.alternativeTriglycerides/HDL-C ratio and high sensible C-reactive protein to the evaluation of cardiovascular risken
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jbpml/paboutj.htm

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
2-s2.0-79958058426.pdf
Tamanho:
174.51 KB
Formato:
Adobe Portable Document Format
Baixar

Coleções

Artigos