Congenital persistent infection with bovine viral diarrhea virus not observed in piglets

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Gomes, Felipe S. [UNESP]
Mechler-Dreibi, Marina L. [UNESP]
Gatto, Igor R. H. [UNESP]
Storino, Gabriel Y. [UNESP]
Pires, Felipe F.B. [UNESP]
Xavier, Eduarda B. [UNESP]
Samara, Samir I. [UNESP]
De Oliveira, Luis Guilherme [UNESP]
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This study was designed to determine whether congenital persistent infection occurs in piglets from gilts experimentally inoculated with bovine viral diarrhea virus type 2 (BVDV-2). Six pregnant gilts were divided into 2 groups, infected (n = 4), and control (n = 2). The gilts were inoculated at 45 days gestation. Piglets were assessed for 35 days following birth with nasal swab and blood sample collections every 72 hours. Reverse transcriptase-polymerase chain reaction (RT-PCR) tests were performed for direct diagnosis of virus in blood and nasal swabs, and virus neutralization was used for antibody detection. Transplacental transmission of BVDV-2 did not occur. Piglets were born free of the virus and did not shed BVDV during the experimental period.
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Canadian Veterinary Journal, v. 60, n. 11, p. 1220-1222, 2019.