Does excess weight interfere with bone mass accumulation during adolescence?

dc.contributor.authorNunes Mosca, Luciana [UNESP]
dc.contributor.authorda Silva, Valéria Nóbrega [UNESP]
dc.contributor.authorGoldberg, Tamara Beres Lederer [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:29:40Z
dc.date.available2014-05-27T11:29:40Z
dc.date.issued2013-06-06
dc.description.abstractObesity and osteoporosis are important global health problems characterized by increasing prevalence with high impact on morbidity and mortality. The objective of this review was to determine whether excess weight during adolescence interferes with bone mass accumulation. If bone mineral gain can be optimized during puberty, adults are less likely to suffer from the devastating complications of osteoporosis. The increased fracture risk in obese children has also been attributed to a lower bone mass for weight compared to non-obese children. Thus, adiposity present in this age group may not result in the protection of bone mass, in contrast to what has been observed in adults. However, studies involving adolescents have reported both protective and detrimental effects of obesity on bone. The results and mechanisms of these interactions are controversial and have not been fully elucidated, a fact highlighting the extreme relevance of this topic and the need to monitor intervening and interactive variables. © 2013 by the authors; licensee MDPI, Basel, Switzerland.en
dc.description.affiliationDiscipline of Adolescent Medicine Department of Pediatrics Botucatu School of Medicine, UNESP, São Paulo State University, Botucatu, SP 18618-970
dc.description.affiliationUnespDiscipline of Adolescent Medicine Department of Pediatrics Botucatu School of Medicine, UNESP, São Paulo State University, Botucatu, SP 18618-970
dc.format.extent2047-2061
dc.identifierhttp://dx.doi.org/10.3390/nu5062047
dc.identifier.citationNutrients, v. 5, n. 6, p. 2047-2061, 2013.
dc.identifier.doi10.3390/nu5062047
dc.identifier.file2-s2.0-84878802412.pdf
dc.identifier.issn2072-6643
dc.identifier.lattes7214834859260397
dc.identifier.orcid0000-0001-7017-766X
dc.identifier.scopus2-s2.0-84878802412
dc.identifier.urihttp://hdl.handle.net/11449/75618
dc.identifier.wosWOS:000320771400013
dc.language.isoeng
dc.relation.ispartofNutrients
dc.relation.ispartofjcr4.196
dc.relation.ispartofsjr1,557
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAdolescents
dc.subjectBone mineral density
dc.subjectObesity
dc.subjectOsteoporosis
dc.subjectOverweight
dc.subjectRisk factors
dc.subject25 hydroxyvitamin D
dc.subjectadiponectin
dc.subjectascorbic acid
dc.subjectcolecalciferol
dc.subjectcopper
dc.subjectergocalciferol
dc.subjectglucose
dc.subjectleptin
dc.subjectmagnesium
dc.subjectparathyroid hormone
dc.subjectphosphorus
dc.subjectprotein
dc.subjectvitamin D
dc.subjectzinc
dc.subjectadipose tissue
dc.subjectanthropometry
dc.subjectbody fat
dc.subjectbone density
dc.subjectbone mass
dc.subjectbone mineral
dc.subjectbone mineralization
dc.subjectcalcium intake
dc.subjectdiet supplementation
dc.subjectdual energy X ray absorptiometry
dc.subjectfat mass
dc.subjectglucose blood level
dc.subjecthuman
dc.subjectinsulin resistance
dc.subjectinsulinemia
dc.subjectlean body weight
dc.subjectobesity
dc.subjectosteopenia
dc.subjectosteoporosis
dc.subjectperipheral quantitative computed tomography
dc.subjectreview
dc.subjectvitamin intake
dc.subjectweight reduction
dc.titleDoes excess weight interfere with bone mass accumulation during adolescence?en
dc.typeArtigo
dcterms.licensehttp://www.mdpi.com/about/openaccess
unesp.author.lattes7214834859260397
unesp.author.orcid0000-0001-7017-766X[3]
unesp.author.orcid0000-0001-5591-019X[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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