Comparison of xylazine and medetomidine as premedicants for cats being anaesthetised with propofol-sevoflurane

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dc.contributor.authorSelmi, A. L.
dc.contributor.authorMendes, G. M.
dc.contributor.authorLins, B. T.
dc.contributor.authorFigueiredo, J. P.
dc.contributor.authorBarbudo-Selmi, G. R.
dc.contributor.institutionUniv Anhembi Morumbi
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionOhio State Univ
dc.date.accessioned2014-05-20T15:29:10Z
dc.date.available2014-05-20T15:29:10Z
dc.date.issued2005-07-30
dc.description.abstractThe effects of premedicating cats with saline, xylazine or medetomidine before anaesthetising them with propofol-sevoflurane were compared. Twenty-four cats were randomly assigned to three groups of eight to receive either 0.25 ml of saline, 0.50 mg/kg of xylazine or 0.02 mg/kg of medetomidine intravenously, and anaesthesia was induced with propofol and maintained with sevoflurane. Medetomidine produced a greater reduction in the induction dose of propofol and fewer adverse postoperative effects than saline or xylazine. Hypoxaemia was observed after induction with propofol in the cats premedicated with saline and xylazine, but not in the cats given medetomidine. The cats treated with medetomidine and xylazine developed profound bradycardia. The blood pressure of the cats premedicated with saline and xylazine decreased, but the blood pressure of the cats premedicated with medetomidine was maintained. The cats premedicated with saline took longer to recover from anaesthesia than the other two groups.en
dc.description.affiliationUniv Anhembi Morumbi, BR-03164110 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationOhio State Univ, Dept Vet Clin Sci, Columbus, OH 43210 USA
dc.description.affiliationUnespUniv Estadual Paulista, BR-18618000 Botucatu, SP, Brazil
dc.format.extent139-+
dc.identifierhttp://veterinaryrecord.bmj.com/content/157/5/139.abstract
dc.identifier.citationVeterinary Record. London: British Veterinary Assoc, v. 157, n. 5, p. 139-+, 2005.
dc.identifier.issn0042-4900
dc.identifier.urihttp://hdl.handle.net/11449/38805
dc.identifier.wosWOS:000231445400011
dc.language.isoeng
dc.publisherBritish Veterinary Assoc
dc.relation.ispartofVeterinary Record
dc.relation.ispartofjcr2.050
dc.relation.ispartofsjr0,464
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleComparison of xylazine and medetomidine as premedicants for cats being anaesthetised with propofol-sevofluraneen
dc.typeArtigo
dcterms.licensehttp://group.bmj.com/products/journals/instructions-for-authors/editorial-policies#copyright-1
dcterms.rightsHolderBritish Veterinary Assoc

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