Effect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intake

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dc.contributor.authorSaad, W. A. [UNESP]
dc.contributor.authorPaulino, M. A. [UNESP]
dc.contributor.authorCamargo, L. A.A. [UNESP]
dc.contributor.authorRenzi, A. [UNESP]
dc.contributor.authorMenani, J. V. [UNESP]
dc.contributor.authorAbrao-Saad, W. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:54:02Z
dc.date.available2022-04-28T19:54:02Z
dc.date.issued1994-12-01
dc.description.abstractSodium chloride intake was studied in male Holtzman rats weighing 250-300 g submitted to electrolytic and chemical lesion of the cell bodies, not fibers of the amygdaloid complex. Sodium chloride (1.5%) intake increased in animals with electrolytic lesion of the corticomedial nucleus of the amygdala. Sodium chloride (1.5%) intake increased after ibotenic acid injection into the corticomedial nucleus of the amygdala to a larger extent (26.6 ± 9.2 to 147.6 ± 34.6 ml/5 days). The results indicate that sodium intake response can be induced by lesions, which involved only cell bodies. The fibers of passage of the corticomedial nucleus of the amygdala produce a water intake less consistent than that induced by ibotenic acid, which is more acute. The results show that cell bodies of this region of the amygdala are involved in the control of sodium chloride intake.en
dc.description.affiliationDpto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, Rua Humaita, 1680, 14801-903 Araraquara, SP
dc.description.affiliationUnespDpto. de Ciencias Fisiologicas Faculdade de Odontologia UNESP, Rua Humaita, 1680, 14801-903 Araraquara, SP
dc.format.extent2903-2907
dc.identifier.citationBrazilian Journal of Medical and Biological Research, v. 27, n. 12, p. 2903-2907, 1994.
dc.identifier.issn0100-879X
dc.identifier.scopus2-s2.0-0028576494
dc.identifier.urihttp://hdl.handle.net/11449/223985
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.sourceScopus
dc.subjectamygdala
dc.subjectelectrolytic lesion
dc.subjectibotenic acid lesion
dc.subjectsodium intake
dc.titleEffect of electrolytic and chemical lesion by ibotenic acid of the amygdala on salt intakeen
dc.typeArtigo

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