NbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effect

dc.contributor.authordos Santos, Giovanny Carvalho [UNESP]
dc.contributor.authorMoreno, Vitor Fernandes [UNESP]
dc.contributor.authorOshiro, Paula Beatriz [UNESP]
dc.contributor.authorda Silva-Filho, Luiz Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T16:55:18Z
dc.date.available2018-12-11T16:55:18Z
dc.date.issued2018-10-18
dc.description.abstractThis paper describes an original one-pot way to synthesize nine new halogenated aminoquinoline derivatives using reactions conducted by niobium pentachloride. Subsequently, we describe an efficient and selective reduction reaction of nitroquinolines using niobium pentachloride and zinc, producing important compounds in the organic synthesis. The results showed that it is an important tool to synthesize these compounds, besides being time- and resources-saving and generating good yields. A quick study of acidochromism was performed.en
dc.description.affiliationLaboratory of Organic Synthesis and Processes (LOSP) São Paulo State University (UNESP) Department of Chemistry School of Sciences
dc.description.affiliationUnespLaboratory of Organic Synthesis and Processes (LOSP) São Paulo State University (UNESP) Department of Chemistry School of Sciences
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2012/24199-8
dc.description.sponsorshipIdFAPESP: 2015/00615-0
dc.description.sponsorshipIdFAPESP: 2016/01599-1
dc.description.sponsorshipIdFAPESP: 2018/14506-7
dc.description.sponsorshipIdCNPq: 302753/2015-0
dc.format.extent6144-6149
dc.identifierhttp://dx.doi.org/10.1016/j.tet.2018.09.003
dc.identifier.citationTetrahedron, v. 74, n. 42, p. 6144-6149, 2018.
dc.identifier.doi10.1016/j.tet.2018.09.003
dc.identifier.issn1464-5416
dc.identifier.issn0040-4020
dc.identifier.scopus2-s2.0-85053054891
dc.identifier.urihttp://hdl.handle.net/11449/171432
dc.language.isoeng
dc.relation.ispartofTetrahedron
dc.relation.ispartofsjr0,800
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAminoquinoline derivatives
dc.subjectNiobium pentachloride
dc.subjectOne-pot reactions
dc.subjectSelective reduction reactions
dc.titleNbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effecten
dc.typeArtigo

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