Frequency of anti-Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Antunes Murata, Fernando Henrique; Ferreira, Marina Neves [UNESP]; Camargo, Natalia Sahyoun; Santos, Gabriela Soria; Junqueira Franco Spegiorin, Ligia Cosentino; Silveira-Carvalho, Aparecida Perpetuo; Pereira-Chioccola, Vera Lucia; Mattos, Luiz Carlos de; Brandao de Mattos, Cinara Cassia

Frequency of anti-Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Arquivos

S0037-86822016000400512.pdf (824.31 KB)

Data

2016-07-01

Autores

Antunes Murata, Fernando Henrique

Ferreira, Marina Neves

Camargo, Natalia Sahyoun

Santos, Gabriela Soria

Junqueira Franco Spegiorin, Ligia Cosentino

Silveira-Carvalho, Aparecida Perpetuo

Pereira-Chioccola, Vera Lucia

Mattos, Luiz Carlos de

Brandao de Mattos, Cinara Cassia

Editor

Soc Brasileira Medicina Tropical

Tipo

Artigo

Direito de acesso

Acesso aberto

Resumo

Introduction: Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests. Methods: An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women. Results: Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG. Conclusions: Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management.