Análise histológica e morfométrica da área cruenta tratada com membrana de silicone: estudo em ratos
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Data
2007-09-01
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Associação Médica Brasileira
Tipo
Artigo
Direito de acesso
Acesso aberto
Resumo
Background. Thin study evaluated the effects of a silicone membrane on the treatment of the raw flesh area in wounds.METHODS. The experimental study was carried out with 30 male Wistar rats divided into three groups: in the G(G) group, the raw area was treated with gauze, in the G(H) group with homograft, and in the G(S) group with a silicone membrane. Animals were sacrificed at fourteen days of postoperative. The studied attributes were body mass variation, histological study quantifed by morphometric analysis evaluating the number of neovessels, fibroblasts, collagen fibers, leucocytes, monocytes; and using a micrometric ruler measurement of the raw area thickness. Data were then submitted to statistical analysis.RESULTS. There was no significant difference between the animals' mass (p=0.0685). Predominance of neovessels (p<0.01), fibroblasts (p<0.001) and thickness of the raw flesh were observed in G(S) animals. There was predominance of leucocytes (p<0.021) and monocytes (p<0.0001) in G(H) animals. Also, no significant difference between the groups as for collagen fibers (p=0.0536) was observed.CONCLUSION. The silicone membrane promoted granulation tissue with a large number of neovessels, fibroblasts and greater thickness.
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Português
Como citar
Revista da Associação Médica Brasileira. São Paulo: Associação Médica Brasileira, v. 53, n. 5, p. 395-400, 2007.
