Influence of different alcohol intake frequencies on alveolar bone loss in adult rats: A sem study
Nenhuma Miniatura disponível
Data
2018-09-01
Orientador
Coorientador
Pós-graduação
Curso de graduação
Título da Revista
ISSN da Revista
Título de Volume
Editor
Tipo
Artigo
Direito de acesso
Acesso restrito
Resumo
Background: Alcohol intake is associated with oral diseases and bone changes including alveolar bone loss in humans and in experimental animals. The main aim of the present study is to assess the effect of long-term alcohol intake, at different frequencies, on periodontal bone loss (PBL) in adult rats. Material and Methods: Thirty-six (36) rats were divided into 3 groups: Control (daily water intake, n=12), daily alcohol intake (20% ethanol, n=12), and social alcohol intake (20% ethanol twice a week, n=12). The rats were sacrificed after 90 days and their right maxillae were removed. Initially, a random portion from each group was analyzed through SEM (scanning electron microscope) to assess surface topography. Next, all pieces were dissected and stained with methylene blue 1% and photographed in stereomicroscope at 10x magnification. The PBL was assessed by measuring the distance between cement-enamel junction and alveolar bone crest. Results: Results showed higher (p=0.0368) alcohol solution amount in the daily intake group than in the twice week intake one. The SEM showed qualitatively flat bone surface in the control group, the social intake group presented surface with few minor hollows, and the daily intake group evidenced increased number and diameter of wells. The comparison between groups showed higher bone loss (p < 0.05) in both frequencies than in the control, but the bone loss was lower (p < 0.05) in the social alcohol intake group than in the daily intake one. Conclusions: Alcohol intake may cause alveolar bone loss in periodontitis-free rats depending on the frequency.
Descrição
Palavras-chave
Idioma
Inglês
Como citar
Journal of Clinical and Experimental Dentistry, v. 10, n. 9, p. e852-e857, 2018.
