Avaliação do colesterol plasmático em coelhos com hipercolesterolemia induzida e tratados com extrato etanólico de própolis

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dc.contributor.authorFernandes, A. A H [UNESP]
dc.contributor.authorAlves, M. J F [UNESP]
dc.contributor.authorBoteon, E. M. [UNESP]
dc.contributor.authorRosa, G. J M [UNESP]
dc.contributor.authorSilva, C. E F [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:24Z
dc.date.available2014-05-27T11:20:24Z
dc.date.issued2002-01-01
dc.description.abstractThe propolis (bee glue) is a product rich in flavonoids, which are known for antioxidant activities, a protective action to the lipoproteins LDL-cholesterol against lipid peroxidation. Because they have antioxidant properties, we investigated the effect of the ethanolic extract propolis on the plasma level of cholesterol in rabbits (Oryctolagus cuniculus) submitted to hypercholesterolaemia. The animals were divided into 4 groups. G 1=received commercial feed and water, G 2=received enriched feed and water, G 3=received enriched feed and ethanol, G 4=received enriched feed and ethanolic extract of propolis. The hypercholesterolaemia was induced with commercial feed enriched with egg yolk. The animals received the ethanolic extract propolis at the concentration of 100 mg/kg daily. Weekly, after fast of 14 hours, the samples of blood were collected from the marginal vein of the ear. The plasma was used for the estimation total cholesterol. From the results obtained, we verified that the ethanolic extract propolis significantly reduced the plasma level cholesterol (109,59 mg/dL, p<0,05), compared to the animals treated with ethanol (331,38 mg/dL), and also to those receiving the commercial feed only, with cholesterol at 269,74 mg/dL.en
dc.description.affiliationDepto. de Quimica e Bioquimica UNESP Campus de Botucatu, Botucatu
dc.description.affiliationUnespDepto. de Quimica e Bioquimica UNESP Campus de Botucatu, Botucatu
dc.format.extent1-5
dc.identifierhttp://www.ibb.unesp.br/Home/Departamentos/Botanica/RBPM-RevistaBrasileiradePlantasMedicinais/artigo_1_v4_n2.pdf
dc.identifier.citationRevista Brasileira de Plantas Medicinais, v. 4, n. 2, p. 1-5, 2002.
dc.identifier.file2-s2.0-0036089077.pdf
dc.identifier.issn1516-0572
dc.identifier.scopus2-s2.0-0036089077
dc.identifier.urihttp://hdl.handle.net/11449/66783
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Plantas Medicinais
dc.relation.ispartofsjr0,199
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectFlavonoids
dc.subjectInduced hypercholesterolaemia
dc.subjectPropolis
dc.subjectRabbits
dc.subjectcholesterol
dc.subjectflavonoid
dc.subjectpropolis
dc.subjectanimal food
dc.subjectanimal model
dc.subjectantioxidant activity
dc.subjectcholesterol blood level
dc.subjectcontrolled study
dc.subjectegg yolk
dc.subjecthypercholesterolemia
dc.subjecthyperlipidemia
dc.subjectlipid peroxidation
dc.subjectnonhuman
dc.subjectrabbit
dc.subjecttreatment outcome
dc.titleAvaliação do colesterol plasmático em coelhos com hipercolesterolemia induzida e tratados com extrato etanólico de própolispt
dc.title.alternativeEffect of the ethanolic própolis on the cholesterol level in rabbits with induced hypercholesterolaemiaen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbpm/paboutj.htm#03
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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