Dietary metyrapone blocks cortisol synthesis in pacu, Piaractus mesopotamicus (Holmberg, 1887), stressed by air exposure

dc.contributor.authorZanuzzo, F. S. [UNESP]
dc.contributor.authorUrbinati, E. C. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T16:19:09Z
dc.date.available2018-11-26T16:19:09Z
dc.date.issued2015-12-01
dc.description.abstractTested was the efficiency of dietary metyrapone (MTP) in the inhibition of cortisol biosynthesis, as a tool to elucidate the effects of this hormone in the tropical fish pacu (Piaractus mesopotamicus H.) during air-exposure-induced stress. Moreover, MTP efficiency was shown to be affected by both the dose and time of administration and that a daily dose of 30 mg kg(-1) body weight for 10 days reduced the levels of circulating cortisol in stressed fish. The tested method of MTP administration, including the concentration and the time of administration, efficiently regulated cortisol synthesis in a non-invasive manner.en
dc.description.affiliationUniv Estadual Paulista, Ctr Aquicultura, UNESP, BR-14884900 Jaboticabal, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Ctr Aquicultura, UNESP, BR-14884900 Jaboticabal, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent1093-1095
dc.identifierhttp://dx.doi.org/10.1111/jai.12916
dc.identifier.citationJournal Of Applied Ichthyology. Hoboken: Wiley-blackwell, v. 31, n. 6, p. 1093-1095, 2015.
dc.identifier.doi10.1111/jai.12916
dc.identifier.issn0175-8659
dc.identifier.urihttp://hdl.handle.net/11449/161107
dc.identifier.wosWOS:000367684400018
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofJournal Of Applied Ichthyology
dc.relation.ispartofsjr0,532
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleDietary metyrapone blocks cortisol synthesis in pacu, Piaractus mesopotamicus (Holmberg, 1887), stressed by air exposureen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell

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