Cervicovaginal levels of human beta defensins during bacterial vaginosis

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dc.contributor.authorNicolau, Nathalia Mayumi Noda
dc.contributor.authorSilva, Márcia Guimarães da
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-07-27T17:39:24Z
dc.date.available2021-07-27T17:39:24Z
dc.date.issued2021-07-22
dc.descriptionA total of 634 women of reproductive age were included in the study. Participants were equally distributed in two groups: according to the classification of vaginal smears according to Nugent criteria in normal (scores 0 to 3) and BV (scores ≥7). Cervicovaginal fluid samples were used for measurements of hBDs1, 2 and 3 levels by enzyme-linked immunosorbent assay (ELISA). Levels of each hBD were compared between the two study groups using Mann-Whitney test, with p-value <0.05 considered as significant. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated for sociodemographic variables and hBD1-3 levels associated with BV a multivariable analysis. Correlation between Nugent score and measured levels of hBDs1-3 were calculated using Spearman’s test.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2012/16800-3
dc.formatExcelpt
dc.identifier.lattes2925946803904487
dc.identifier.lattes4940791909535775
dc.identifier.orcid0000-0002-2392-6127
dc.identifier.orcid00000002-4663-7926
dc.identifier.urihttp://hdl.handle.net/11449/213676
dc.language.isoeng
dc.rights.accessRightsAcesso aberto
dc.rights.holderNathalia Mayumi Noda Nicolaupt
dc.subjectHuman beta defensinsen
dc.subjectBacterial vaginosisen
dc.titleCervicovaginal levels of human beta defensins during bacterial vaginosisen
dc.typeDado de pesquisa
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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