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Cervicovaginal levels of human beta defensins during bacterial vaginosis

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dc.contributor.authorNicolau, Nathalia Mayumi Noda
dc.contributor.authorSilva, Márcia Guimarães da
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-07-27T17:39:24Z
dc.date.available2021-07-27T17:39:24Z
dc.date.issued2021-07-22
dc.descriptionA total of 634 women of reproductive age were included in the study. Participants were equally distributed in two groups: according to the classification of vaginal smears according to Nugent criteria in normal (scores 0 to 3) and BV (scores ≥7). Cervicovaginal fluid samples were used for measurements of hBDs1, 2 and 3 levels by enzyme-linked immunosorbent assay (ELISA). Levels of each hBD were compared between the two study groups using Mann-Whitney test, with p-value <0.05 considered as significant. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated for sociodemographic variables and hBD1-3 levels associated with BV a multivariable analysis. Correlation between Nugent score and measured levels of hBDs1-3 were calculated using Spearman’s test.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2012/16800-3
dc.formatExcelpt
dc.identifier.lattes2925946803904487
dc.identifier.lattes4940791909535775
dc.identifier.orcid0000-0002-2392-6127
dc.identifier.orcid00000002-4663-7926
dc.identifier.urihttp://hdl.handle.net/11449/213676
dc.language.isoeng
dc.rights.accessRightsAcesso abertopt
dc.rights.holderNathalia Mayumi Noda Nicolaupt
dc.subjectHuman beta defensinsen
dc.subjectBacterial vaginosisen
dc.titleCervicovaginal levels of human beta defensins during bacterial vaginosisen
dc.typeDado de pesquisapt
dspace.entity.typePublication
relation.isDepartmentOfPublicationa245add5-d5dd-4133-b280-ff763c412c47
relation.isDepartmentOfPublication.latestForDiscoverya245add5-d5dd-4133-b280-ff763c412c47
relation.isOrgUnitOfPublicationa3cdb24b-db92-40d9-b3af-2eacecf9f2ba
relation.isOrgUnitOfPublication.latestForDiscoverya3cdb24b-db92-40d9-b3af-2eacecf9f2ba
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentPatologia - FMBpt

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