A new tropane alkaloid and other constituents of Erythroxylum rimosum (Erythroxylaceae)
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2013-05-01
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A new tropane alkaloid, named the 7β-acetoxy-3β,6β- dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-α-l-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-α- arabinopyranoside, quercetin-3-O-β-arabinopyranoside, quercetin-3-β- glucopyranoside, kaempferol, quercetin-3-O-β-galactopyranoside, β-sitosterol, α-amyrin, β-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data. © 2013 Phytochemical Society of Europe.
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Acetylcholinesterase inhibition, Erythroxylaceae, Erythroxylum rimosum, Flavonoids, Triterpenes, Tropane alkaloid, 7beta acetoxy 3beta,6beta dibenzoyloxytropane, acetylcholinesterase, alpha amyrin, beta amyrin, catechin, epicatechin, Erythroxylum rimosum extract, ester derivative, glucopyranoside, kaempferol, kaempferol 3 O alpha levo arabinofuranoside, kaempferol derivative, methanol, plant extract, quercetin 3 beta glucopyranoside, quercetin 3 O alpha arabinofuranoside, quercetin 3 O alpha arabinopyranoside, quercetin 3 O beta galactopyranoside, quercetin derivative, sitosterol, tropane alkaloid, unclassified drug, cholinesterase inhibition, controlled study, drug structure, electrospray mass spectrometry, enzyme inhibition, heteronuclear multiple bond correlation, infrared radiation, nuclear magnetic resonance, plant leaf, priority journal, proton nuclear magnetic resonance, Erythroxylum
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Inglês
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Phytochemistry Letters, v. 6, n. 2, p. 232-235, 2013.
