Turbinatine, a potential key intermediate in the biosynthesis of corynanthean-type indole alkaloids

Nenhuma Miniatura disponível

Data

2003-07-01

Orientador

Coorientador

Pós-graduação

Curso de graduação

Título da Revista

ISSN da Revista

Título de Volume

Editor

Amer Chemical Soc

Tipo

Editorial

Direito de acesso

Acesso restrito

Resumo

Extraction of the leaves of Chimarrhis turbinata has led to the isolation of turbinatine (1), a new corynanthean-type indole alkaloid, besides four known indole alkaloids, strictosidine, 5alpha-carboxystrictosidine, vallesiachotamine, and isovallesiachotamine. The structural determination of 1 was based on 1D and 2D spectroscopic data. An evaluation of the DNA-damaging activities of the isolates was performed by means of a bioassay using mutant strains of Saccharomyces cerevisiae, which indicated these compounds were weakly active.

Descrição

Palavras-chave

Idioma

Inglês

Como citar

Journal of Natural Products. Washington: Amer Chemical Soc, v. 66, n. 7, p. 1017-1021, 2003.

Itens relacionados

Financiadores