Circulating thyroid hormone levels in young pregnant rats and their fetuses: Effect of malnutrition

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dc.contributor.authorMello, M. A. Rostom de
dc.contributor.authorOliveira-Filho, R. M.
dc.contributor.authorCury, L.
dc.contributor.authorSouza Valle, L. B.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T05:32:28Z
dc.date.available2014-05-27T05:32:28Z
dc.date.issued1989-01-01
dc.description.abstractIn order to evaluate some factors likely to be involved in the maternal and fetal growth impairment due to alimentary protein deficiency, the circulating levels of triiodothyronine (T 3) and thyroxine (T 4) were studied in 4 young (45-day-old) female rat groups: control and malnourished, both nonpregnant and pregnant; similarly schedules groups were studied using adult (100-day-old) rats. Circulating levels of T 4 were higher in nonpregnant, malnourished young rats in their corresponding controls. T 3 levels were higher in young malnourished animals and lower in adult malnourished animals, nonpregnant or pregnant, as compared to controls. Pups from young malnourished mothers showed significantly lower birth weights than those from controls. The present results suggest that there are age differences in thyroid function, as affected by protein-calorie malnutrition in pregnant and non-pregnant rats. On the other hand, the circulating thyroid hormone levels were not importantly affected by the mother dietary protein restriction under our experimental conditions.en
dc.description.affiliationUniversidade de São Paulo, Departamento de Farmacologia, Instituto de Ciências Biomédicas, São Paulo, Brasil
dc.description.affiliationUniversidade de São Paulo, Departamento de Fisiologia & Biofísica, Instituto de Ciências Biomédicas, São Paulo, Brasil
dc.description.affiliationUniversidade Estadual Paulista (UNESP), Departamento de Educação Física, Instituto de Biociências, Rio Claro, Brazil
dc.description.affiliationUnespUniversidade Estadual Paulista (UNESP), Departamento de Educação Física, Instituto de Biociências, Rio Claro, Brazil
dc.format.extent181-187
dc.identifierhttp://dx.doi.org/10.1159/000177535
dc.identifier.citationAnnals of Nutrition and Metabolism, v. 33, n. 3, p. 181-187, 1989.
dc.identifier.doi10.1159/000177535
dc.identifier.issn0250-6807
dc.identifier.scopus2-s2.0-0024319229
dc.identifier.urihttp://hdl.handle.net/11449/130543
dc.identifier.wosWOS:A1989AN17100006
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofAnnals of Nutrition and Metabolism
dc.relation.ispartofjcr3.051
dc.relation.ispartofsjr1,317
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectThyroid hormone
dc.subjectAnimal experiment
dc.subjectFemale
dc.subjectGrowth
dc.subjectNonhuman
dc.subjectPregnancy
dc.subjectPriority journal
dc.subjectProtein restriction
dc.subjectRat
dc.subjectAnimal
dc.subjectBody Weight
dc.subjectDiet
dc.subjectFemale
dc.subjectFetus
dc.subjectGestational Age
dc.subjectNutrition Disorders
dc.subjectPregnancy
dc.subjectPregnancy, Animal
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.subjectThyroid Hormones
dc.subjectThyroxine
dc.subjectTriiodothyronine
dc.titleCirculating thyroid hormone levels in young pregnant rats and their fetuses: Effect of malnutritionen
dc.typeArtigo
dcterms.licensehttp://www.karger.com/Services/RightsPermissions
dcterms.rightsHolderKarger
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Rio Claropt

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