Iron oxide nanoparticles for biomedical applications: A perspective on synthesis, drugs, antimicrobial activity, and toxicity

dc.contributor.authorArias, Laís Salomão [UNESP]
dc.contributor.authorPessan, Juliano Pelim [UNESP]
dc.contributor.authorVieira, Ana Paula Miranda [UNESP]
dc.contributor.authorDe Lima, Taynara Maria Toito
dc.contributor.authorDelbem, Alberto Carlos Botazzo [UNESP]
dc.contributor.authorMonteiro, Douglas Roberto
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversity of Western São Paulo (UNOESTE)
dc.date.accessioned2018-12-11T17:21:20Z
dc.date.available2018-12-11T17:21:20Z
dc.date.issued2018-06-09
dc.description.abstractMedical applications and biotechnological advances, including magnetic resonance imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug delivery, have strongly benefited from employing iron oxide nanoparticles (IONPs) due to their remarkable properties, such as superparamagnetism, size and possibility of receiving a biocompatible coating. Ongoing research efforts focus on reducing drug concentration, toxicity, and other side effects, while increasing efficacy of IONPs-based treatments. This review highlights the methods of synthesis and presents the most recent reports in the literature regarding advances in drug delivery using IONPs-based systems, as well as their antimicrobial activity against different microorganisms. Furthermore, the toxicity of IONPs alone and constituting nanosystems is also addressed.en
dc.description.affiliationDepartment of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (Unesp)
dc.description.affiliationGraduate Program in Dentistry (GPD-Master’s Degree) University of Western São Paulo (UNOESTE)
dc.description.affiliationUnespDepartment of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (Unesp)
dc.identifierhttp://dx.doi.org/10.3390/antibiotics7020046
dc.identifier.citationAntibiotics, v. 7, n. 2, 2018.
dc.identifier.doi10.3390/antibiotics7020046
dc.identifier.file2-s2.0-85049511275.pdf
dc.identifier.issn2079-6382
dc.identifier.scopus2-s2.0-85049511275
dc.identifier.urihttp://hdl.handle.net/11449/176556
dc.language.isoeng
dc.relation.ispartofAntibiotics
dc.relation.ispartofsjr1,063
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectBiotechnology
dc.subjectDrug delivery
dc.subjectIron oxide nanoparticles
dc.subjectMagnetic nanoparticles
dc.titleIron oxide nanoparticles for biomedical applications: A perspective on synthesis, drugs, antimicrobial activity, and toxicityen
dc.typeResenha
unesp.author.lattes0421571920582994[5]
unesp.author.orcid0000-0002-8159-4853[5]

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