Bone regeneration with recombinant human bone morphogenetic protein 2: a systematic review
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2018-03-01
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Springer
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Aim The aim of this work was to perform a systematic literature review on the clinical application of rhBMP-2 in bone reconstruction prior to placing implants. Materials and Methods A PUBMED search was made about the subject and nine clinical trials were selected according to strict inclusion criteria. Results Overall success rates of bone regeneration with rhBMP-2 was 81.4% and success of implants placed was 87.4%. Most frequent adverse events were pain, edema and erythema. Conclusion It was concluded that the treatment with rhBMP-2 foi satisfactory in most cases and the placement of dental implants in the bone regenerated with rhBMP-2 is feasible.
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Journal Of Maxillofacial & Oral Surgery. New Delhi: Springer India, v. 17, n. 1, p. 13-18, 2018.
