ROLE OF ADRENERGIC PATHWAYS OF THE MEDIAL PREOPTIC AREA IN ANGII-INDUCED WATER-INTAKE AND RENAL EXCRETION IN RATS

dc.contributor.authorBastos, R.
dc.contributor.authorSaad, W. A.
dc.contributor.authorMenani, José Vanderlei [UNESP]
dc.contributor.authorRenzi, Antonio [UNESP]
dc.contributor.authorSilveira, JEN
dc.contributor.authorCamargo, LAD
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:27:47Z
dc.date.available2014-05-20T15:27:47Z
dc.date.issued1994-02-04
dc.description.abstractIn this study, we investigated the participation of adrenergic neurotransmission in angiotensin II- (ANGII)-induced water intake and urinary electrolyte excretion by means of injection of the alpha(1)-, alpha(2)-, and beta-adrenoceptor antagonists and ANGII into the medial preoptic area (MPOA) in rats. Prazosin (an alpha(1)-adrenergic antagonist) antagonized the water ingestion, Na+, K+ and urine excretion induced by ANGII, whereas yohimbine (an alpha(2)-adrenergic antagonist) enhanced the Na+, K+ and urine excretion induced by ANGII. Propranolol (a nonselective beta-adrenoceptor blocker) antagonized the water ingestion and enhanced the Na+ and urine excretion induced by ANGII. Previous treatment with prazosin reduced the presser responses to ANGII, whereas yohimbine had opposite effects. Previous injection of propranolol produced no effects in the presser responses to ANGII. These results suggest that the adrenergic neurotransmission in the MPOA may actively participate in ANGII-induced dipsogenesis, natriuresis, kaliuresis and diuresis in a process that involves alpha(1)-, alpha(2)-, and beta-adrenoceptors.en
dc.description.affiliationPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 ARARAQUARA,SP,BRAZIL
dc.description.affiliationUnespPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 ARARAQUARA,SP,BRAZIL
dc.format.extent81-86
dc.identifierhttp://dx.doi.org/10.1016/0006-8993(94)90178-3
dc.identifier.citationBrain Research. Amsterdam: Elsevier B.V., v. 636, n. 1, p. 81-86, 1994.
dc.identifier.doi10.1016/0006-8993(94)90178-3
dc.identifier.issn0006-8993
dc.identifier.lattes1023597870118105
dc.identifier.lattes6551236936295697
dc.identifier.urihttp://hdl.handle.net/11449/37719
dc.identifier.wosWOS:A1994MV32400010
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBrain Research
dc.relation.ispartofjcr3.125
dc.relation.ispartofsjr1,404
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectWATER INTAKEpt
dc.subjectFLUID BALANCEpt
dc.subjectELECTROLYTE BALANCEpt
dc.subjectAV3V REGIONpt
dc.subjectADRENERGIC RECEPTORpt
dc.titleROLE OF ADRENERGIC PATHWAYS OF THE MEDIAL PREOPTIC AREA IN ANGII-INDUCED WATER-INTAKE AND RENAL EXCRETION IN RATSen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes1023597870118105
unesp.author.lattes6551236936295697
unesp.author.orcid0000-0003-1167-4441[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição: