Synthesis parameters for control of mesoporous silica nanoparticles (MSNs)

MSNs are excellent host matrices for molecules and biomolecules, making this material very promising for several nanotechnological applications in industry scale, chemical engineering, environmental, medicine and biology; for instance, as catalysts; adsorbents of heavy metals for depollution; drug delivery systems; and biomarkers, respectively. Here, we report our efforts to obtain MSNs type MCM-41, with controlled particle size (100 to 150 nm), spherical shape, no agglomeration, high surface area, a high pore volume and hexagonal arrangement by full optimization of procedure, studying the influence of parameters as reactants concentrations, temperature and reaction time. Herein, we discussed all performed experiments, the nanoparticles formation, as well as the results are presented and argued according literature data.