Publicação:
Studies of natural killer cells in patients with paracoccidioidomycosis

dc.contributor.authorPeraçoli, M. T.S. [UNESP]
dc.contributor.authorSoares, A. M.V.C. [UNESP]
dc.contributor.authorMendes, R. P. [UNESP]
dc.contributor.authorMarques, S. A. [UNESP]
dc.contributor.authorPereira, P. C.M. [UNESP]
dc.contributor.authorRezkallah-Iwasso, M. T. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T07:20:29Z
dc.date.available2022-04-29T07:20:29Z
dc.date.issued1991-01-01
dc.description.abstractThe number and activity of natural killer (NK) cells were studied in 34 untreated patients with paracoccidioidomycosis, 20 with the chronic form of the disease and 14 with the acute form. NK cells were detected with monoclonal antibody Leu-11c and the cytotoxic activity was measured using a single cell assay against K562 target cells. Both groups of patients had an increased number of circulating NK cells, their cytotoxic activity being significantly lower than in the healthy controls. These findings may be of importance in the immunological disturbances associated with paracoccidioidomycosis since NK cells exert important immune effector functions and may play a role in resistance against Paracoccidioides brasiliensis. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.en
dc.description.affiliationDepartment of Microbiology and Immunology, Institute of Biological Sciences, São Paulo State University (UNESP)
dc.description.affiliationDepartment of Infectious and Parasitologic Diseases, Dermatology and Radiology, School of Medicine, UNESP, Botucatu, São Paulo
dc.description.affiliationUnespDepartment of Microbiology and Immunology, Institute of Biological Sciences, São Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Infectious and Parasitologic Diseases, Dermatology and Radiology, School of Medicine, UNESP, Botucatu, São Paulo
dc.format.extent373-380
dc.identifierhttp://dx.doi.org/10.1080/02681219180000601
dc.identifier.citationMedical Mycology, v. 29, n. 6, p. 373-380, 1991.
dc.identifier.doi10.1080/02681219180000601
dc.identifier.issn1369-3786
dc.identifier.scopus2-s2.0-84907133851
dc.identifier.urihttp://hdl.handle.net/11449/227862
dc.language.isoeng
dc.relation.ispartofMedical Mycology
dc.sourceScopus
dc.titleStudies of natural killer cells in patients with paracoccidioidomycosisen
dc.typeArtigo
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.departmentDermatologia e Radioterapia - FMBpt
unesp.departmentMicrobiologia e Imunologia - IBBpt

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