Homeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in rats

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dc.contributor.authorSpin-Neto, Rubens [UNESP]
dc.contributor.authorBelluci, Marina Montosa [UNESP]
dc.contributor.authorSakakura, Celso Eduardo
dc.contributor.authorScaf, Gulnara [UNESP]
dc.contributor.authorPepato, Maria Teresa [UNESP]
dc.contributor.authorMarcantonio, Elcio [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:31:57Z
dc.date.accessioned2014-05-20T13:45:29Z
dc.date.available2013-09-30T18:31:57Z
dc.date.available2014-05-20T13:45:29Z
dc.date.issued2010-10-01
dc.description.abstractIntroduction: This study evaluated the effect of Symphytum officinale in homeopathic potency (6cH), on the removal torque and radiographic bone density around titanium implants, inserted in rats tibiae.Methods: Implants were placed in male rat tibiae, and the animals randomized to two groups (Control and S. officinale 6cH treated), which were evaluated at 7, 14, 28 and 56 days post-implantation. Radiographic bone density was measured at 6 points around the implant, using digital radiographic images, when implants were inserted and at sacrifice. Removal torque of the implants was also evaluated.Results: Both removal torque and radiographic bone density evaluation showed that S. officinale 6cH treatment enhanced bone formation around the micro-implants, mainly at 14 days. At 56 days, the radiographic bone density was higher in the treated group.Conclusions: We conclude that S. officinale 6cH enhances, principally at the early stages of osseointegration, bone formation around titanium implants in rats' tibiae, based on radiographic and mechanical analysis. Homeopathy (2010) 99, 249-254.en
dc.description.affiliationUniv Estadual Paulista, Araraquara Dent Sch, Dept Periodontol, BR-14801903 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Araraquara Dent Sch, Dept Radiol, BR-14801903 São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Sch Pharmaceut Sci Araraquara, Dept Clin Biochem, Araraquara, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Araraquara Dent Sch, Dept Periodontol, BR-14801903 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Araraquara Dent Sch, Dept Radiol, BR-14801903 São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Sch Pharmaceut Sci Araraquara, Dept Clin Biochem, Araraquara, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent249-254
dc.identifierhttp://dx.doi.org/10.1016/j.homp.2010.08.002
dc.identifier.citationHomeopathy. Oxford: Elsevier B.V., v. 99, n. 4, p. 249-254, 2010.
dc.identifier.doi10.1016/j.homp.2010.08.002
dc.identifier.issn1475-4916
dc.identifier.urihttp://hdl.handle.net/11449/16002
dc.identifier.wosWOS:000283835700004
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofHomeopathy
dc.relation.ispartofjcr1.524
dc.relation.ispartofsjr0,678
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectRadiographyen
dc.subjectBone densityen
dc.subjectTorqueen
dc.subjectSymphytum officinaleen
dc.subjectOsseointegrationen
dc.subjectTitanium implantsen
dc.subjectExperimentalen
dc.subjectHomeopathyen
dc.titleHomeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in ratsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.orcid0000-0002-9660-4524[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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