Efeitos da corticoterapia materna nos valores hemogasométricos de cordeiros nascidos a termo e prematuros

dc.contributor.authorFeitosa, Francisco Leydson Formiga [UNESP]
dc.contributor.authorávila, Larissa Gabriela
dc.contributor.authorBovino, Fernanda [UNESP]
dc.contributor.authorSantos, Guilherme Gonçalves Fabretti [UNESP]
dc.contributor.authorMendes, Luiz Cláudio Nogueira [UNESP]
dc.contributor.authorPeiró, Juliana Regina [UNESP]
dc.contributor.authorPerri, Sílvia Helena Venturolli [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Mato Grosso do Sul (UFMS)
dc.date.accessioned2018-12-11T17:14:27Z
dc.date.available2018-12-11T17:14:27Z
dc.date.issued2017-05-01
dc.description.abstractThe aim of the study was to evaluate blood gas parameters of full-term and premature lambs from birth to 48 hours of life. Four experimental groups were formed: NDG (normal delivery group - lambs vaginally delivered, n=15, average of 146-day gestation); NDEXG (normal delivery with dexamethasone group - lambs vaginally delivered whose mothers received 16 mg of dexamethasone at 141 days of gestation, n=8, average of 143-day gestation); PRE (premature lambs born by cesarean section at 138 days of gestation, n=10) and PREDEX (premature lambs born by cesarean section at 138 days gestation, whose mothers received 16mg of dexamethasone two days before, n=9). Immediately after birth, lambs from all groups showed respiratory acidosis (low pH and high pCO2), most obviously in premature animals. The concentration of HCO3 - was lower between 15 and 60 minutes of life, especially in PRE and PREDEX groups with subsequent increase in M24h. The values of base excess were lower in premature lambs, which showed abdominal breathing, severe dyspnea and lots of lung fluid. The stabilization of acid-base balance occurred in all animals during the first 24 hours of life. Dexamethasone had a positive effect on the clinical condition of the premature lambs, resulting in adequate ventilation and tissue perfusion, which guaranteed higher survival rate.en
dc.description.affiliationDepartamento de Clínica Cirurgia e Reprodução Animal Faculdade de Medicina Veterinária Universidade Estadual Paulista (Unesp-Araçatuba), Rua Clóvis Pestana 793
dc.description.affiliationFaculdade de Medicina Veterinária e Zootecnia (FAMEZ) Universidade Federal de Mato Grosso do Sul (UFMS), Av. Costa e Silva s/n, Cidade Universitária
dc.description.affiliationPós-Graduando em Ciência Animal Faculdade de Medicina Veterinária Unesp-Araçatuba, Rua Clóvis Pestana 793
dc.description.affiliationDocente do Departamento de Apoio à Produção e Saúde Animal Faculdade de Medicina Veterinária Unesp-Araçatuba, Rua Clóvis Pestana 793
dc.description.affiliationUnespDepartamento de Clínica Cirurgia e Reprodução Animal Faculdade de Medicina Veterinária Universidade Estadual Paulista (Unesp-Araçatuba), Rua Clóvis Pestana 793
dc.description.affiliationUnespPós-Graduando em Ciência Animal Faculdade de Medicina Veterinária Unesp-Araçatuba, Rua Clóvis Pestana 793
dc.description.affiliationUnespDocente do Departamento de Apoio à Produção e Saúde Animal Faculdade de Medicina Veterinária Unesp-Araçatuba, Rua Clóvis Pestana 793
dc.format.extent521-525
dc.identifierhttp://dx.doi.org/10.1590/S0100-736X2017000500016
dc.identifier.citationPesquisa Veterinaria Brasileira, v. 37, n. 5, p. 521-525, 2017.
dc.identifier.doi10.1590/S0100-736X2017000500016
dc.identifier.fileS0100-736X2017000500521.pdf
dc.identifier.issn1678-5150
dc.identifier.issn0100-736X
dc.identifier.lattes2232625970712015
dc.identifier.scieloS0100-736X2017000500521
dc.identifier.scopus2-s2.0-85028614934
dc.identifier.urihttp://hdl.handle.net/11449/175117
dc.language.isopor
dc.relation.ispartofPesquisa Veterinaria Brasileira
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAcid-base balance
dc.subjectBlood gas analysis
dc.subjectBlood gas values
dc.subjectCorticotherapy
dc.subjectDexamethasone
dc.subjectHemogasometry
dc.subjectLambs
dc.subjectPrematurity
dc.titleEfeitos da corticoterapia materna nos valores hemogasométricos de cordeiros nascidos a termo e prematurospt
dc.title.alternativeEffects of maternal blood gas values corticotherapy of Lambs born at term and prematureen
dc.typeArtigo
unesp.author.lattes2232625970712015

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