Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles

dc.contributor.authorCorral Nuñez, Camila [UNESP]
dc.contributor.authorCovarrubias, Cristian
dc.contributor.authorFernandez, Eduardo
dc.contributor.authorOliveira Junior, Osmir Batista de [UNESP]
dc.contributor.institutionFacultad de Odontología
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionLaboratorio de Nanobiomateriales
dc.date.accessioned2018-12-11T16:46:57Z
dc.date.available2018-12-11T16:46:57Z
dc.date.issued2017-03-01
dc.description.abstractObjective To prepare nanocomposite cements based on the incorporation of bioactive glass nanoparticles (nBGs) into BiodentineTM (BD, Septodent, Saint-Maur-des-Fosses Cedex, France) and to assess their bioactive properties. Material and Methods nBGs were synthesised by the sol-gel method. BD nanocomposites (nBG/BD) were prepared with 1 and 2% nBGs by weight; unmodified BD and GC Fuji IX (GIC, GC Corporation, Tokyo, Japan) were used as references. The in vitro ability of the materials to induce apatite formation was assessed in SBF by X-ray diffraction (XRD), attenuated total reflectance with Fourier transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis. BD and nBG/BD were also applied to dentine discs for seven days; the morphology and elemental composition of the dentine-cement interface were analysed using SEM-EDX. Results One and two percent nBG/BD composites accelerated apatite formation on the disc surface after short-term immersion in SBF. Apatite was detected on the nBG/BD nanocomposites after three days, compared with seven days for unmodified BD. No apatite formation was detected on the GIC surface. nBG/BD formed a wider interfacial area with dentine than BD, showing blockage of dentine tubules and Si incorporation, suggesting intratubular precipitation. Conclusions The incorporation of nBGs into BD improves its in vitro bioactivity, accelerating the formation of a crystalline apatite layer on its surface after immersion in SBF. Compared with unmodified BD, nBG/BD showed a wider interfacial area with greater Si incorporation and intratubular precipitation of deposits when immersed in SBF.en
dc.description.affiliationUniversidad de Chile Facultad de Odontología Departamento de Odontología Restauradora
dc.description.affiliationUniversidade Estadual Paulista - UNESP Faculdade de Odontologia Departmento de Odontologia Restauradora
dc.description.affiliationUniversidad de Chile Facultad de Odontología Instituto de Investigación en Ciencias Odontológicas Laboratorio de Nanobiomateriales
dc.description.affiliationUnespUniversidade Estadual Paulista - UNESP Faculdade de Odontologia Departmento de Odontologia Restauradora
dc.format.extent177-185
dc.identifierhttp://dx.doi.org/10.1590/1678-77572016-0209
dc.identifier.citationJournal of Applied Oral Science, v. 25, n. 2, p. 177-185, 2017.
dc.identifier.doi10.1590/1678-77572016-0209
dc.identifier.fileS1678-77572017000200177.pdf
dc.identifier.issn1678-7765
dc.identifier.issn1678-7757
dc.identifier.lattes0170241211219616
dc.identifier.orcid0000-0002-2153-9887
dc.identifier.scieloS1678-77572017000200177
dc.identifier.scopus2-s2.0-85017536248
dc.identifier.urihttp://hdl.handle.net/11449/169636
dc.language.isoeng
dc.relation.ispartofJournal of Applied Oral Science
dc.relation.ispartofsjr0,645
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectApatite-forming ability
dc.subjectBioactive glass
dc.subjectBioactivity
dc.subjectBiodentine
dc.subjectNanocomposites
dc.titleEnhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticlesen
dc.typeArtigo
unesp.author.lattes0170241211219616[4]
unesp.author.orcid0000-0002-2153-9887[4]

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