Dietary whey protein lessens several risk factors for metabolic diseases: a review

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Sousa, Gabriela T. D.
Lira, Fabio S.
Rosa, Jose C.
de Oliveira, Erick P. [UNESP]
Oyama, Lila M.
Santos, Ronaldo V.
Pimentel, Gustavo D.

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Biomed Central Ltd.


Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.



Whey protein, Obesity, Type 2 diabetes mellitus, Appetite, Inflammation, Hypertension

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Lipids In Health and Disease. London: Biomed Central Ltd., v. 11, p. 9, 2012.