Compostos derivados de taurina, processo de preparação e composições contendo ditos derivados

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Data

2014-02-27

Autores

Vizioli, Ednir de Oliveira
Chin, Chung Man [UNESP]
Menegon, Renato Farina
Blau, Lorena
Santos, Jean Leandro dos [UNESP]
Longo, Maria do Carmo [UNESP]

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Instituto Nacional de Propriedade Industrial (INPI)

Resumo

The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity. In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I): in which R means the component with non-steroidal anti inflammatory activity. In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI. The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity.

Descrição

Processo: PI0800951-1
Processo: WO2009124371
Número de publicação: US2014057959 (A1)
Número de aplicação: US201314035690

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