Baldi, Bruno GuedesFabro, Alexandre TodorovicFranco, Andreia Craveiro [UNESP]Machado, Marília Helena C. [UNESP]Prudente, Robson Aparecido [UNESP]Franco, Estefânia Thomé [UNESP]Marrone, Sergio Ribeiro [UNESP]Vale, Simone Alves do [UNESP]Cezare, Talita Jacon [UNESP]Moraes, Marcelo Padovani de ToledoFerreira, Eloara Vieira MachadoAlbuquerque, André Luis PereiraSawamura, Marcio Valente YamadaTanni, Suzana Erico [UNESP]2023-03-012023-03-012022-01-01Jornal Brasileiro de Pneumologia, v. 48, n. 3, 2022.1806-37561806-3713http://hdl.handle.net/11449/240933This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials–ReBEC; identifier: RBR-8j9kqy [http://www. ensaiosclinicos.gov.br]).engBiopsyCOVID-19COVID-19/pathologyPulmonary fibrosisRespiratory function testsArtigo10.36416/1806-3756/e202104382-s2.0-85129406799