Verissimo, Lourena MafraAgnez Lima, Lucymara FassarelaMonte Egito, Lucila CarmemOliveira, Anselmo Gomes de [UNESP]Tabosa do Egito, E. Socrates2014-05-202014-05-202010-06-01Journal of Drug Targeting. London: Informa Healthcare, v. 18, n. 5, p. 333-342, 2010.1061-186Xhttp://hdl.handle.net/11449/7818The concept of gene therapy involves the experimental transfer of a therapeutic gene into an individual's cells and tissues to replace an abnormal gene aiming to treat a disease, or to use the gene to treat a disease just like a medicine, improving the clinical status of a patient. The achievement of a foreigner nucleic acid into a population of cells requires its transfer to the target. Therefore, it is essential to create carriers (vectors) that transfer and protect the nucleic acid until it reaches the target. The obvious disadvantages of the use of viral vectors have directed the research for the development of a nonviral organized system such as emulsions. In fact, recently, there has been an increase of interest in its use in biotechnology as a nonviral vector for gene therapy. This review focuses on the progress of cationic emulsions and the improvement of the formulations, as a potential delivery system for gene therapy.</.333-342engCationic emulsionsgene transfectiongene therapycarrier systemsdelivery systemsArtigo10.3109/10611860903434019WOS:000277364900001Acesso restrito9114495952533044