Gobbo, Luis Alberto [UNESP]Judice, Pedro B.Hetherington-Rauth, MeganSardinha, Luis B.Dos Santos, Vanessa Ribeiro [UNESP]2021-06-252021-06-252020-11-01International Journal Of Environmental Research And Public Health. Basel: Mdpi, v. 17, n. 21, 13 p., 2020.http://hdl.handle.net/11449/209648Aging causes some unfavorable morphological and functional changes, such as the decline in bone mineral density (BMD) and physical function. Moderate-to-vigorous physical activity (MVPA) and sedentary time seem to be related with these alterations, but the impact of distinct patterns remains unclear. The aim of this study was to cross-sectionally and prospectively assess the association between objectively measured MVPA and sedentary patterns (bouts and breaks) with BMD and physical function in older adults. The study considered 151 Brazilians (aged >= 60 years), out of which 68 participants completed 2-year follow-up measurements. MVPA and sedentary patterns were measured by means of accelerometry, BMD-(total proximal femur and lumbar spine (L1-L4)) by means of dual-energy X-ray absorptiometry (DXA), and physical function-by means of physical tests. In older women, sedentary bouts >60 min were inversely associated with handgrip strength (beta = -2.03, 95% CI: from -3.43 to -0.63). The prospective analyses showed that changes in sedentary bouts (20 to 30 min and >60 min) were inversely associated with changes in the lumbar spine's BMD (beta = -0.01, 95% CI: from -0.01 to -0.00 and beta = -0.03, 95% CI: from -0.06 to -0.01) and the lumbar spine's T-score (beta = -0.06, 95% CI: from -0.10 to -0.01 and beta = -0.27, 95% CI: from -0.49 to -0.04), respectively. In older women, sedentary patterns are cross-sectionally associated with handgrip strength and prospectively associated with BMD independent of MVPA.13engaccelerationbone healthexercisephysical healthsedentary livingArtigo10.3390/ijerph17218198WOS:000588919600001